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Caspase 9

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Also Known As:
Apoptotic Protease Activating Factor 3; Caspase-9; ICE-LAP6 Protein; ICE-Like Apoptotic Protease 6; Pro-Caspase-9; Procaspase-9; ICE LAP6 Protein; ICE Like Apoptotic Protease 6; Pro Caspase 9; Procaspase 9
Networked: 1110 relevant articles (19 outcomes, 98 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Delivoria-Papadopoulos, Maria: 13 articles (08/2012 - 07/2004)
2. Mishra, Om P: 12 articles (08/2010 - 07/2004)
3. Ashraf, Qazi M: 8 articles (12/2008 - 03/2007)
4. Kim, Sung-Hoon: 7 articles (07/2015 - 10/2004)
5. Schulze-Osthoff, Klaus: 7 articles (04/2012 - 10/2006)
6. Dent, Paul: 6 articles (10/2013 - 05/2002)
7. Chung, Jing-Gung: 6 articles (10/2013 - 01/2009)
8. Grant, Steven: 5 articles (10/2013 - 05/2002)
9. Yang, Jai-Sing: 5 articles (09/2012 - 01/2009)
10. Wang, Shaomeng: 5 articles (05/2012 - 05/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Ischemia
3. Anoxia (Hypoxia)
4. Breast Neoplasms (Breast Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Caspase 3 (Caspase-3)
2. Cytochromes c (Cytochrome c)
3. Caspase 8 (Caspase-8)
4. Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
5. Proteins (Proteins, Gene)
6. Reactive Oxygen Species (Oxygen Radicals)
7. benzyloxycarbonyl- leucyl- glutamyl- histidyl- aspartic acid fluoromethyl ketone
8. Messenger RNA (mRNA)
9. Glucose (Dextrose)
10. Caspases

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Diet Therapy (Therapy, Diet)
4. Aftercare (After-Treatment)
5. Electroacupuncture