|1.||Wang, Jian: 6 articles (11/2015 - 06/2013)|
|2.||Rousseau, Adrien: 6 articles (01/2014 - 01/2011)|
|3.||Alpy, Fabien: 6 articles (01/2014 - 01/2008)|
|4.||Yang, Fan: 5 articles (11/2015 - 10/2014)|
|5.||Tomasetto, Catherine: 5 articles (01/2014 - 01/2008)|
|6.||Mi, Xiao-Yi: 4 articles (11/2015 - 10/2007)|
|7.||Rio, Marie-Christine: 4 articles (12/2013 - 01/2008)|
|8.||Ren, Hua-Yan: 3 articles (11/2015 - 02/2015)|
|9.||Mi, Xiaoyi: 3 articles (05/2015 - 06/2013)|
|10.||Ouyang, Wenjun: 2 articles (09/2015 - 03/2015)|
|1.||Breast Neoplasms (Breast Cancer)
05/01/2015 - "The aim of the present study was to analyze the correlation, expression and nuclear and cytoplasmic localizations of TRAF4 and Girdin in breast cancer tissues. "
10/01/2014 - "In this study, we identified β-catenin as a TRAF4-binding protein, have shown that TRAF4 enhanced expression of β-catenin, and found that TRAF4 mediated the translocation of β-catenin from the cytoplasm to the nucleus, thereby facilitating activation of the Wnt signaling pathway in breast cancer. "
08/01/2015 - "TRAF4 upregulated PRMT5 expression, which occurred predominantly in the nucleus, on which TRAF4 promotion of cell proliferation in breast cancer is mainly dependent. "
08/01/2015 - "PRMT5 and TRAF4 were both overexpressed in breast cancer tissues and cells, and we found that PRMT5 binds to the zinc finger structures in TRAF4 by coimmunoprecipitation and Western blotting. "
08/01/2015 - "We examined TRAF4 and PRMT5 expression by immunohistochemistry and found that their expression is positively correlated in breast cancer. "
12/01/2014 - "Although numerous studies have suggested that there is elevated TRAF4 expression in human cancer, it is still unknown in which oncogenic pathway TRAF4 is mainly implicated. "
09/01/2014 - "In the present study, we found that TRAF4 was overexpressed in cancer cells, and RNA interference (RNAi)-mediated gene knockdown of TRAF4 decreased cell growth, cell migration and invasion. "
09/21/2015 - "Thus, IL-17-induced Steap4-p63 expression forms a positive feedback loop through p63-mediated TRAF4 expression, driving IL-17-dependent sustained activation of the TRAF4-ERK5 axis for keratinocyte proliferation and tumor formation. "
01/01/2014 - "These findings shed new light on the role of TRAF4 in cancer progression; they provide a novel link between lipid metabolism and cancer progression and support the notion that TRAF4 could be a relevant target for cancer therapies. "
01/01/2014 - "We recently found that TRAF4 impedes TJ formation/stability and favors cell migration, 2 hallmarks of cancer progression. "
10/01/2007 - "This study was to investigate the expression of TRAF4 in normal breast, breast carcinoma tissue, and cell lines with different invasive abilities. "
09/01/2015 - "MLPA assay revealed gene copy gains of MYC, CCND1, ZNF703, CDH1, and TRAF4 in 50% or greater of the apocrine carcinomas, whereas gene copy losses frequently affected BRCA2 (75%), ADAM9 (54%), and BRCA1 (46%). "
01/01/2014 - "[TRAF4, a multifaceted protein involved in carcinoma progression]."
01/01/2008 - "In vivo, TRAF4 is consistently found at TJs in normal human mammary epithelia as well as in well-differentiated in situ carcinomas. "
10/01/2007 - "The expression of TRAF4 in 70 specimens of breast carcinoma and 14 specimens of normal breast tissues was detected by SP immunohistochemistry. "
|4.||Neoplasm Metastasis (Metastasis)
05/01/2015 - "Furthermore, coexpression of TRAF4 and Girdin was highest in tissue samples from patients with lymph node metastases. "
01/01/2014 - "In addition TRAF4 contributes to the TGF-β-induced epithelial-mesenchymal transition (EMT), metastasis, and p53 destabilization. "
01/01/2014 - "This study aimed to explore the expression of TRAF4 in osteosarcoma tissues and cells, the correlation of TRAF4 to clinical pathology of osteosarcoma, as well as the role and mechanism of TRAF4 in osteosarcoma metastasis. "
12/01/2014 - "This review highlights TGF-β-induced SMAD-dependent signaling and non-SMAD signaling as the major pathways regulated by TRAF4 involved in breast cancer metastasis. "
03/01/2014 - "The few genes that showed differences between primary tumor and metastasis (PRDM14, MED1, CCNE1, TRAF4, MTDH, CDH1) have been implicated in the development of therapy resistance."
|5.||Osteosarcoma (Osteogenic Sarcoma)
12/01/2014 - "These results indicate that TRAF4 regulated osteosarcoma cell growth in vitro and in vivo, and offers a candidate molecular target for osteosarcoma prevention and therapy."
12/01/2014 - "Using the technique of RNA interference, the expression of TRAF4 in the human osteosarcoma Saos-2 cell line was shown to be downregulated. "
12/01/2014 - "TRAF4 is overexpressed in osteosarcoma tissues and osteosarcoma cells. "
12/01/2014 - "Knockdown of TRAF4 expression suppresses osteosarcoma cell growth in vitro and in vivo."
01/01/2014 - "This work suggests that TRAF4 might be an important target in osteosarcoma."
|1.||Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
|2.||TNF Receptor-Associated Factor 2 (TRAF2)
|3.||TNF Receptor-Associated Factor 6 (TRAF6)
|4.||Small Interfering RNA (siRNA)
|5.||Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)
|6.||TNF Receptor-Associated Factor 4
|7.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||Proteins (Proteins, Gene)
|9.||Messenger RNA (mRNA)
|10.||Staphylococcal Protein A (A, Protein)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Prostatectomy (Retropubic Prostatectomy)