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CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)

An APOPTOSIS-regulating protein that is structurally related to CASPASE 8 and competes with CASPASE 8 for binding to FAS ASSOCIATED DEATH DOMAIN PROTEIN. Two forms of CASP8 and FADD-like apoptosis regulating protein exist, a long form containing a caspase-like enzymatically inactive domain and a short form which lacks the caspase-like domain.
Also Known As:
FLIP-S; Casper Protein; FLICE-Inhibitory Protein; FLICE-Inhibitory Protein Long Form; FLICE-Inhibitory Protein Short Form; FLIP (Cellular); FLIP-L; FLIP-L Protein; FLIP-S Protein; CASP8 and FADD Like Apoptosis Regulating Protein; FLICE Inhibitory Protein; FLICE Inhibitory Protein Long Form; FLICE Inhibitory Protein Short Form; FLIP L Protein; FLIP S Protein
Networked: 187 relevant articles (4 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kwon, Taeg Kyu: 5 articles (02/2015 - 08/2010)
2. Longley, Daniel B: 5 articles (01/2013 - 05/2007)
3. Liu, Xiangguo: 5 articles (01/2012 - 12/2006)
4. Safa, Ahmad R: 5 articles (06/2011 - 05/2006)
5. Dent, Paul: 4 articles (06/2014 - 09/2008)
6. Grant, Steven: 4 articles (06/2014 - 09/2008)
7. Johnston, Patrick G: 4 articles (01/2013 - 05/2007)
8. Chaudhary, Preet M: 4 articles (06/2011 - 01/2005)
9. Matta, Hittu: 4 articles (06/2011 - 01/2005)
10. Panner, Amith: 4 articles (06/2010 - 10/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Pancreatic Neoplasms (Pancreatic Cancer)
3. Colonic Neoplasms (Colon Cancer)
4. Multiple Sclerosis
5. Autoimmune Diseases (Autoimmune Disease)

Related Drugs and Biologics

1. CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)
2. Caspase 8 (Caspase-8)
3. Proteins (Proteins, Gene)
4. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5. Proteasome Endopeptidase Complex (Proteasome)
6. Small Interfering RNA (siRNA)
7. Caspase 3 (Caspase-3)
8. Protein C
9. Inhibitor of Apoptosis Proteins
10. Apoptosis Regulatory Proteins

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Aftercare (After-Treatment)