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Receptor-Interacting Protein Serine-Threonine Kinases

A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
Also Known As:
RIP (Receptor Interacting Protein); RIP Serine-Threonine Kinase; Receptor Interacting Protein RIP; Receptor-Interacting Protein Serine-Threonine Kinase 1; Receptor-Interacting Protein Serine-Threonine Kinase 3; Kinase, RIP Serine-Threonine; Kinases, RIP Serine-Threonine; RIP Serine Threonine Kinase; RIP Serine Threonine Kinases; Receptor Interacting Protein Serine Threonine Kinase 1; Receptor Interacting Protein Serine Threonine Kinase 3; Receptor Interacting Protein Serine Threonine Kinases; Serine-Threonine Kinase, RIP; Serine-Threonine Kinases, RIP; RIP Serine-Threonine Kinases
Networked: 42 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chan, Francis Ka-Ming: 3 articles (05/2014 - 12/2003)
2. Miller, Joan W: 3 articles (09/2012 - 12/2010)
3. Murakami, Yusuke: 3 articles (09/2012 - 12/2010)
4. Vavvas, Demetrios G: 3 articles (09/2012 - 12/2010)
5. Bertin, John: 2 articles (05/2014 - 10/2013)
6. Kaiser, William J: 2 articles (05/2014 - 10/2013)
7. Gough, Peter J: 2 articles (05/2014 - 10/2013)
8. Mocarski, Edward S: 2 articles (05/2014 - 10/2013)
9. Hisatomi, Toshio: 2 articles (09/2012 - 12/2010)
10. Liu, Zheng-Gang: 2 articles (04/2012 - 03/2003)

Related Diseases

1. Necrosis
2. Atherosclerosis
3. Anoxia (Hypoxia)
4. Acute Liver Failure (Fulminant Hepatic Failure)
5. Rupture

Related Drugs and Biologics

1. Caspase 3 (Caspase-3)
2. Niacinamide (Nicotinamide)
3. Phosphotransferases (Kinase)
4. Reactive Oxygen Species (Oxygen Radicals)
5. Mitochondrial DNA (mtDNA)
6. Cathepsins
7. Acetaminophen (Paracetamol)
8. Caspase 8 (Caspase-8)
9. Proteins (Proteins, Gene)
10. Type I Tumor Necrosis Factor Receptors