CRADD Signaling Adaptor Protein (RIP-Associated Protein With a Death Domain)

A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.
Also Known As:
RIP-Associated Protein With a Death Domain; RIP Associated Protein With a Death Domain; Caspase and Rip Adaptor with Death Domain Protein; RAIDD Signaling Adaptor Protein
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Bio-Agent Context: Research Results