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Apolipoprotein C-III

A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Also Known As:
Apo C-III; Apo C-III-2; ApoC-III; Apolipoprotein C-III-0; Apolipoprotein C-III-1; Apolipoprotein CIII; Sialyl Apo C-III; Sialyl Apolipoprotein C-III; Apo C III; Apo C III 2; Apo C-III, Sialyl; ApoC III; Apolipoprotein C III; Apolipoprotein C III 0; Apolipoprotein C III 1; Apolipoprotein C-III, Sialyl; Sialyl Apo C III; Sialyl Apolipoprotein C III
Networked: 322 relevant articles (13 outcomes, 28 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sacks, Frank M: 17 articles (07/2015 - 04/2003)
2. Chan, Dick C: 11 articles (10/2015 - 08/2002)
3. Barrett, P Hugh R: 11 articles (10/2015 - 08/2002)
4. Watts, Gerald F: 11 articles (10/2015 - 08/2002)
5. Alaupovic, Petar: 6 articles (05/2015 - 02/2005)
6. Girelli, Domenico: 5 articles (01/2013 - 09/2002)
7. Pizzolo, Francesca: 5 articles (01/2013 - 09/2002)
8. Olivieri, Oliviero: 5 articles (01/2013 - 09/2002)
9. Ooi, Esther M M: 5 articles (04/2011 - 05/2008)
10. Kawakami, Akio: 5 articles (11/2010 - 08/2006)

Related Diseases

1. Hypertriglyceridemia
2. Dyslipidemias (Dyslipidemia)
3. Infection
4. Fever (Fevers)
5. Body Weight (Weight, Body)

Related Drugs and Biologics

1. Lipoproteins (Lipoprotein)
2. Apolipoproteins E (ApoE)
3. Apolipoprotein A-I (Apolipoprotein A1)
4. Triglycerides (Triacylglycerol)
5. Proteins (Proteins, Gene)
6. 3' Untranslated Regions (3' UTR)
7. Cholesterol
8. Apolipoproteins C (ApoC)
9. Lipoprotein Lipase (Diacylglycerol Lipase)
10. Adiponectin

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Highly Active Antiretroviral Therapy (HAART)
3. Kidney Transplantation
4. Peritoneal Dialysis
5. Subcutaneous Injections