Transmembrane Activator and CAML Interactor Protein

A tumor necrosis factor receptor superfamily member found expressed on peripheral B-LYMPHOCYTES. It has specificity for B-CELL MATURATION ANTIGEN and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13.

Also Known As:

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Derfalvi, Beata: 1 article (11/2021)
2.	Malik, Aniko: 1 article (11/2021)
3.	Muise, Aleixo: 1 article (11/2021)
4.	Stringer, Elizabeth: 1 article (11/2021)
5.	Vandersteen, Anthony: 1 article (11/2021)
6.	Warner, Neil: 1 article (11/2021)
7.	van Limbergen, Johan: 1 article (11/2021)
8.	Boban, Jasmina M: 1 article (12/2018)
9.	Brkić, Snežana V: 1 article (12/2018)
10.	Lendak, Dajana F: 1 article (12/2018)

Related Diseases

1.	Multiple Organ Failure (MODS) 12/31/2018 - "The aim of this study was to evaluate the prognostic value of A Proliferation Inducing Ligand (APRIL) and soluble Transmembrane Activator and CAML Interactor Protein (sTACI), the main B cell function regulators, in prediction of MODS development within the first 48 h after admission to intensive care unit, among septic patients. "
2.	Common Variable Immunodeficiency 06/01/2011 - "Heterozygous deleterious mutations in the gene encoding the tumor necrosis factor receptor superfamily member 13b (TNFRSF13B), or transmembrane activator and CAML interactor (TACI), have been associated with the development of common variable immunodeficiency. " 09/01/2009 - "Coding variants in tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) have been implicated in common variable immunodeficiency (CVID), but the functional effects of such mutations in relation to the development of the disease have not been entirely established. " 11/01/2021 - "Whole exome sequencing revealed a heterozygous TNFRSF13B (Tumor Necrosis Factor Receptor Superfamily Member 13B, or Transmembrane Activator and Calcium-modulating cyclophilin ligand Interactor, TACI) gene variant, which is associated with common variable immunodeficiency and the development of autoimmune diseases. "
3.	Autoimmune Diseases (Autoimmune Disease) 11/01/2021 - "Whole exome sequencing revealed a heterozygous TNFRSF13B (Tumor Necrosis Factor Receptor Superfamily Member 13B, or Transmembrane Activator and Calcium-modulating cyclophilin ligand Interactor, TACI) gene variant, which is associated with common variable immunodeficiency and the development of autoimmune diseases. "

Related Drugs and Biologics

1.	Ligands
2.	Cyclophilins (Cyclophilin)
3.	Calcium