|1.||Botham, K M: 6 articles (11/2011 - 07/2000)|
|2.||Redgrave, T G: 6 articles (12/2005 - 02/2001)|
|3.||Vaziri, Nosratola D: 5 articles (04/2014 - 11/2009)|
|4.||Botham, Kathleen M: 5 articles (10/2009 - 11/2002)|
|5.||Fujioka, Yoshio: 5 articles (06/2007 - 12/2003)|
|6.||Watts, G F: 5 articles (12/2005 - 02/2001)|
|7.||Yamashita, Shizuya: 4 articles (01/2014 - 06/2007)|
|8.||Ishikawa, Yuichi: 4 articles (06/2007 - 12/2003)|
|9.||Martins, I J: 4 articles (12/2005 - 05/2001)|
|10.||Bravo, E: 4 articles (08/2005 - 03/2001)|
04/01/2000 - "Rabbits which are susceptible to diabetes induced atherogenesis had significantly greater intimal retention of chylomicron remnants compared to rats. "
05/04/2002 - "Ageing is associated with impaired clearance of chylomicron remnants, postprandial hypertriglyceridaemia, and hence, atherosclerosis, which we propose is linked directly to loss of permeability of the liver sieve because of defenestration associated with pseudocapillarisation. "
10/01/2005 - "This study proposes a mechanism of atherosclerosis induced by chylomicron remnants."
09/01/2003 - "This study provides further evidence to support a role of chylomicron remnants in the development of atherosclerosis."
06/01/2013 - "Chylomicron remnants can penetrate into the artery wall, where they can initiate atherogenesis. "
06/01/1985 - "This study was conducted to determine whether chylomicron remnants accumulate in the plasma of patients with "endogenous" hypertriglyceridemia. "
02/05/1991 - "Impaired clearance of chylomicron remnants possibly contributes to the hypertriglyceridemia of WHHL rabbits and to accelerated atherogenesis when the function of LDL receptors is defective."
08/01/1992 - "In conclusion, 1) fasting triglyceride levels are a more powerful indicator of the postprandial lipid response than basal HDL cholesterol in subjects with low HDL cholesterol levels; 2) patients with low HDL cholesterol levels do not preferentially accumulate chylomicron remnants after a meal unless they have coexisting hypertriglyceridemia; and 3) abnormalities in the levels of triglyceride-rich particles post-prandially are unlikely to be responsible for the increased incidence of atherosclerosis in low HDL patients who are normotriglyceridemic."
06/01/1985 - "Postchallenge plasma lipoprotein retinoids: chylomicron remnants in endogenous hypertriglyceridemia."
05/16/1983 - "Since apolipoprotein B-48 appears to be a marker for remnants of intestinal particles, its slower removal than that of apolipoprotein B-100 in severe hypertriglyceridemia suggests that one metabolic defect associated with the hyperchylomicronemia is defective removal of chylomicron remnants."
07/01/1999 - "We conclude that T4 enhances the clearance of chylomicron remnants in normolipidemic patients with hypothyroidism."
07/01/1999 - "Thyroxine replacement therapy enhances clearance of chylomicron remnants in patients with hypothyroidism."
02/01/1981 - "Effects of hypothyroidism and cholesterol feeding on the clearance of chylomicron remnants in vivo and by rat hepatocyte monolayers."
02/01/1981 - "Thus, the study suggests that chylomicron remnant uptake by the liver is not inhibited by hypothyroidism per se but by the cholesterol accumulation in hepatocytes that is the consequence of cholesterol and bile acid feeding of the rats. "
01/01/2013 - " Such altered serum levels of ApoB-48 in patients with OH and SH may be related to the disturbed metabolism of chylomicron remnants in patients with hypothyroidism."
08/26/2003 - "The findings suggest that the apoE2-induced dyslipidemia is not merely the result of substitution of R158 for C but results from increased secretion of a triglyceride-enriched VLDL that cannot undergo lipolysis, inhibition of LpL activity, and impaired clearance of chylomicron remnants. "
05/01/2001 - "Chylomicron remnant metabolism in familial dyslipidemias studied with a remnant-like emulsion breath test."
01/01/2005 - "Delayed clearance of chylomicron remnants from the blood occurs in a number of dyslipidemias associated with premature atherosclerosis development, and the potentially atherogenic effects of the particles would clearly be enhanced in these circumstances. "
06/01/2010 - "Intestinally derived chylomicron remnants (CM-r) are also thought to contribute to atherogenic dyslipidemia during insulin resistance. "
02/01/2012 - "GLP-1-mediated control of postprandial chylomicron production may be lost in type 2 diabetes in which the incretin response is impaired and in which associated dyslipidemia involves an excess of atherogenic chylomicron remnants. "
|5.||Cardiovascular Diseases (Cardiovascular Disease)
11/01/2003 - "Impaired clearance of chylomicron remnants is associated with increased risk of atherosclerosis and cardiovascular disease. "
09/01/1999 - "Enhanced clearance of chylomicrons and chylomicron remnants by HRT may contribute to the protective effect of estrogens against cardiovascular disease in normolipemic postmenopausal women."
09/01/2005 - "Decreases in circulating levels of LDL and chylomicron remnants seen in humans with the consumption of margarine phytosterols are possibly due to their effect on lipid production in cells and would therefore reduce the risk of developing cardiovascular disease."
05/01/2015 - "Familial dysbetalipoproteinemia (FD), also known as type III hyperlipoproteinemia, is a genetic dyslipidemia characterized by elevated very low density lipoprotein (VLDL) and chylomicron remnant particles that confers increased risk of cardiovascular disease (CVD). "
|2.||LDL Receptors (LDL Receptor)
|6.||Vitamin A (Retinol)
|7.||Lipase (Acid Lipase)
|8.||Apolipoprotein A-I (Apolipoprotein A1)
|9.||Lipoprotein Lipase (Diacylglycerol Lipase)