|1.||Christensen, Lars P: 5 articles (01/2011 - 05/2006)|
|2.||Choi, Yung Hyun: 4 articles (01/2007 - 12/2004)|
|3.||Kim, Nam Deuk: 4 articles (01/2007 - 12/2004)|
|4.||Jung, Jee H: 3 articles (01/2007 - 12/2004)|
|5.||Jung, Sang Hoon: 2 articles (03/2014 - 03/2013)|
|6.||Pan, Cheol-Ho: 2 articles (03/2014 - 03/2013)|
|7.||Nho, Chu Won: 2 articles (03/2014 - 03/2013)|
|8.||Park, Cheol: 2 articles (01/2007 - 07/2006)|
|9.||Bae, Song-Ja: 2 articles (07/2006 - 12/2004)|
|10.||Choi, Hye Joung: 2 articles (02/2006 - 12/2004)|
01/01/2011 - "However, to the best of our knowledge, no study concerning the inhibitory effects of the two polyacetylenes on cell growth of human promyelocytic leukemia cells has been reported. "
11/01/2011 - "Carrots contain beneficial agents, such as β-carotene and polyacetylenes, which could be effective in the treatment of leukemia. "
07/01/2006 - "Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation."
01/01/2007 - "Inhibition of cyclooxygenase-2 and telomerase activities in human leukemia cells by dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp."
|2.||Colonic Neoplasms (Colon Cancer)
03/01/2013 - "A polyacetylene-rich extract from Gymnaster koraiensis strongly inhibits colitis-associated colon cancer in mice."
02/07/2007 - "The polyacetylene falcarinol, isolated from carrots, has been shown to be protective against chemically induced colon cancer development in rats, but the mechanisms are not fully understood. "
|3.||Melanoma (Melanoma, Malignant)
11/01/2013 - "In this study, polyacetylene 1 demonstrated a more potent cytotoxic activity than 2 in the tumour cell lines examined, and cytotoxicity was found to be comparable to a commercial drug (p > 0.05) in melanoma cells. "
08/01/2007 - "Compounds 1, 2, 3, 5, and 6 showed moderate activity against tumor cell lines (human small lung cancer cell line A549, melanoma SK-Mel-2, and mouse melanoma B16F1) with IC(50) values in the range of 7.4 - 30 microg/mL. Compounds 7 and 9, including other polyacetylenes, showed strong activity against the fungus Trichophyton (MIC: 5 - 10 microg/mL)."
02/08/2006 - "We investigated the possible mechanisms by which petrotetrayndiol A, a polyacetylene from the sponge Petrosia sp., exerts its anti-proliferative activity in cultured SK-MEL-2 human melanoma cells. "
12/01/2004 - "Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells."
03/19/2014 - "Dietary polyacetylenes from various foods have been receiving attention as promising cancer chemopreventive agents. "
06/07/2006 - "The effect of these polyacetylenes towards human cancer cells, their human bioavailability and their ability to reduce tumour formation in a mammalian in vivo model indicates that they may also provide benefits for health. "
10/01/1993 - "We evaluated a number of terthiophenes and polyynes, from the Asteraceae, for biological activities against microorganisms, viruses, and tumor cells, with and without the aid of UVA (long wavelength ultraviolet) radiation. "
01/01/2011 - "In addition, the cytotoxicity of falcarinol type polyacetylenes towards human cancer cells, bioavailability, and their potential anticancer effect in vivo indicates that these compounds may contribute to the health effects of certain vegetables and hence could be important nutraceuticals. "
01/01/2007 - "Dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp., is known to exhibit significant selective cytotoxic activity against several human cancer cell lines. "
07/27/2011 - "Most of the index compounds selected, particularly the ergostane-type triterpenoids and polyacetylenes, possess good anti-inflammation activity. "
12/01/2012 - "Besides decursin, DA and DOH, other chemical components in AGN such as polysaccharides and polyacetylenes have been reported to exert anti-cancer and anti-inflammation activities as well. "
|6.||Cyclooxygenase 2 (Cyclooxygenase-2)
|8.||Ethylene Glycol (Monoethylene Glycol)
|9.||Telomerase (Telomerase Reverse Transcriptase)