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CD137 Antigens

A member of the tumor necrosis factor receptor superfamily that is specific for 4-1BB LIGAND. It is found in a variety of immune cell types including activated T-LYMPHOCYTES; NATURAL KILLER CELLS; and DENDRITIC CELLS. Activation of the receptor on T-LYMPHOCYTES plays a role in their expansion, production of cytokines and survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Also Known As:
Antigens, CD137; 4-1BB Receptor; CD137 Antigen; TNFRSF9 Receptor; 4 1BB Receptor; 4 1BB Receptors; Antigen, CD137; Receptor, 4-1BB; Receptor, TNFRSF9; Receptors, 4-1BB; 4-1BB Receptors; Tumor Necrosis Factor Receptor Superfamily, Member 9
Networked: 15 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Watts, Tania H: 2 articles (01/2012 - 01/2009)
2. Lin, Gloria H Y: 2 articles (01/2012 - 01/2009)
3. Schabowsky, Rich-Henry: 2 articles (01/2012 - 05/2010)
4. Yolcu, Esma S: 2 articles (01/2012 - 05/2010)
5. Shirwan, Haval: 2 articles (01/2012 - 05/2010)
6. Madireddi, Shravan: 2 articles (01/2012 - 05/2010)
7. Sharma, Rajesh K: 2 articles (01/2012 - 05/2010)
8. Srivastava, Abhishek K: 2 articles (01/2012 - 05/2010)
9. Chen, Shu-Hsia: 2 articles (03/2011 - 04/2004)
10. Yuan, Yi: 1 article (01/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
3. Human Influenza (Influenza)
4. Obesity
5. Inflammation

Related Drugs and Biologics

1. 4-1BB Ligand (4 1BB Ligand)
2. Interleukin-2 (IL2)
3. Carbon Monoxide
4. TNF Receptor-Associated Factor 1
5. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
6. Transforming Growth Factor alpha (TGF-alpha)
7. Macrophage Colony-Stimulating Factor
8. Biological Markers (Surrogate Marker)
9. Mucins
10. Immunoglobulins (Immunoglobulin)

Related Therapies and Procedures

1. Immunotherapy