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Osteoprotegerin

A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Also Known As:
FDCR-1 Protein; Follicular Dendritic Cell-Derived Receptor-1; OCIF Protein; Tumor Necrosis Factor Receptor 11b; FDCR 1 Protein; Follicular Dendritic Cell Derived Receptor 1; Osteoclastogenesis Inhibitory Factor; Receptors, Tumor Necrosis Factor, Member 11b; Tumor Necrosis Factor Receptor Superfamily, Member 11b
Networked: 2491 relevant articles (39 outcomes, 386 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ueland, Thor: 25 articles (12/2018 - 07/2002)
2. Hofbauer, Lorenz C: 23 articles (01/2019 - 08/2002)
3. Aukrust, Pål: 22 articles (08/2019 - 11/2004)
4. Terpos, Evangelos: 22 articles (01/2019 - 08/2003)
5. Flyvbjerg, Allan: 16 articles (12/2014 - 03/2003)
6. Bjerre, Mette: 15 articles (01/2020 - 08/2010)
7. Schoppet, Michael: 15 articles (01/2013 - 09/2002)
8. Dunstan, C R: 15 articles (01/2007 - 01/2000)
9. Kostenuik, Paul J: 14 articles (11/2018 - 12/2002)
10. Hofbauer, L C: 13 articles (04/2012 - 01/2000)

Related Diseases

1. Bone Resorption
2. Osteoporosis
3. Rheumatoid Arthritis
4. Pain (Aches)
5. Vascular Calcification

Related Drugs and Biologics

1. Ligands
2. RANK Ligand
3. Diphosphonates (Bisphosphonates)
4. Osteopontin
5. Osteocalcin
6. Alkaline Phosphatase
7. Atorvastatin (Lipitor)
8. Zoledronic Acid (Zometa)
9. Denosumab
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Therapeutics
2. Ovariectomy (Oophorectomy)
3. Low-Level Light Therapy (LLLT)
4. Moxibustion
5. Renal Dialysis (Hemodialysis)