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TNF-Related Apoptosis-Inducing Ligand Receptors

Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
Also Known As:
Receptors, TNF-Related Apoptosis-Inducing Ligand; APO2 Receptor; CD261 Antigen; CD262 Antigen; CD264 Antigen; DCR2 Receptor; DR4 Receptor; DR5 Receptor; Death Receptor-4; Death Receptor-5; Receptor, TRAIL-1; Receptor, TRAIL-2; Receptor, TRAIL-4; Receptors, Tumor Necrosis Factor, Member 10a; Receptors, Tumor Necrosis Factor, Member 10d; TNF-Related Apoptosis-Inducing Ligand Receptor 2; TRAIL Receptor 1; TRAIL Receptor 2; TRAIL Receptor 4; TRAIL Receptors; Tumor Necrosis Factor Receptor Superfamily, Member 10a; Tumor Necrosis Factor Receptor Superfamily, Member 10b; Antigen, CD261; Antigen, CD262; Antigen, CD264; Death Receptor 4; Death Receptor 5; Receptor 4, TRAIL; Receptor, APO2; Receptor, DCR2; Receptor, DR4; Receptor, DR5; Receptor, TRAIL 1; Receptor, TRAIL 2; Receptor, TRAIL 4; Receptor-4, Death; Receptors, TNF Related Apoptosis Inducing Ligand; TNF Related Apoptosis Inducing Ligand Receptor 2; TNF Related Apoptosis Inducing Ligand Receptors; TRAIL-1 Receptor; TRAIL-2 Receptor; TRAIL-4 Receptor; Decoy Receptor 2, Tumor Necrosis Factor; Receptors, TRAIL; Receptors, Tumor Necrosis Factor, Member 10; Receptors, Tumor Necrosis Factor, Member 10b; Tumor Necrosis Factor Receptor Superfamily, Member 10
Networked: 813 relevant articles (23 outcomes, 98 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sun, Shi-Yong: 18 articles (01/2021 - 10/2004)
2. Buchsbaum, Donald J: 16 articles (01/2018 - 04/2006)
3. Liu, Xiangguo: 15 articles (08/2016 - 10/2004)
4. Khuri, Fadlo R: 14 articles (12/2015 - 10/2004)
5. Yue, Ping: 13 articles (12/2015 - 10/2004)
6. Sakai, Toshiyuki: 13 articles (08/2014 - 08/2004)
7. Yagita, Hideo: 13 articles (11/2013 - 02/2004)
8. Zhou, Tong: 12 articles (01/2021 - 04/2006)
9. Zheng, Dexian: 11 articles (06/2021 - 12/2006)
10. Walczak, Henning: 10 articles (01/2021 - 12/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Pancreatic Neoplasms (Pancreatic Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Colorectal Neoplasms (Colorectal Cancer)
5. Adenocarcinoma

Related Drugs and Biologics

1. Monoclonal Antibodies
2. Proteins (Proteins, Gene)
3. tigatuzumab
4. Immunoglobulin G (IgG)
5. drozitumab
6. Caspase 3 (Caspase-3)
7. Ligands
8. Antibodies
9. Death Domain Receptors
10. conatumumab

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Lasers (Laser)
4. Oral Administration
5. Radiotherapy