Nocturnal Enuresis (Bedwetting)

07/01/2004 - "CONCLUSIONS: Alarms are the most effective treatment for nocturnal enuresis in children, but desmopressin may be considered for temporary relief."
02/01/2008 - "In this issue Ferrara et al. present an important placebo-controlled, three-arm, double-blind, double-dummy, study on the treatment of nocturnal enuresis, demonstrating that homotoxicology is superior to placebo but less effective than desmopressin"
07/01/2004 - "The study included 259 children suffering from PNE (92 girls, 167 boys, aged 5-18 years): 42 children were relieved from bedwetting after urotherapy and 136 children had a complete response to desmopressin"
06/01/2000 - "CONCLUSION: DDAVP treatment is more effective than RCT in decreasing the number of wet nights in childhood nocturnal enuresis, but not so effective in children with a low functional bladder capacity"
10/01/2004 - "Desmopressin seems to be effective in the treatment of primary nocturnal enuresis while on therapy but during the long-term follow-up, all cases relapsed."
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09/01/1992 - "In children, the drug is prescribed most frequently (56%) for conditions outside the licensed indications, particularly nocturnal enuresis, a condition for which the efficacy of Ditropan has not been established"
11/01/2007 - "PURPOSE: We assessed prospectively the efficacy of holding exercises and/or antimuscarinics (oxybutynin chloride and placebo) for increasing maximum voided volume in prepubertal children with monosymptomatic nocturnal enuresis"
11/01/2007 - "CONCLUSIONS: In the treatment of children with monosymptomatic nocturnal enuresis maximum voided volume can be increased significantly through holding exercises, but not with oxybutynin chloride alone"
12/01/2002 - "OBJECTIVES: To evaluate children with refractory monosymptomatic nocturnal enuresis to determine whether detrusor overactivity (DOA) plays a role in 4 weeks of unsuccessful treatment with retention control training (RCT); whether an increase in bladder capacity can eventually be obtained by RCT plus oxybutynin; and whether the increase in capacity is the primary key to success"
01/01/1993 - "Sixty-three children with persistent nocturnal enuresis were urodynamically assessed and subsequently treated with oxybutynin chloride"
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01/01/1999 - "Imipramine therapy was given to 10 of the 17 patients with symptoms of urinary frequency, urgency and nocturnal enuresis with a significantly symptomatic improvement in 9 of these patients"
06/01/1997 - "Nocturnal enuresis was observed in 4 children who responded favorably to imipramine hydrochloride therapy"
04/01/1996 - "The aim of this study was to investigate any existing urinary or serum factor differences between 9 children with primary nocturnal enuresis and six age and sex matched controls and to see if therapy with Imipramine could modify these parameters"
01/01/1985 - "Since imipramine has a beneficial effect in the treatment of nocturnal enuresis, the present study was carried out to investigate a possible association between alteration in 3H-imipramine binding parameters in enuretics in comparison to nonenuretic control subjects"
01/01/1963 - "A controlled trial of imipramine in the treatment of nocturnal enuresis in mentally subnormal patients."
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02/01/1986 - "The results showed that diclofenac sodium was significantly more effective than placebo in the treatment of nocturnal enuresis."
02/01/1986 - "The prostaglandin synthesis inhibitor diclofenac sodium has been compared with a placebo in the treatment of primary nocturnal enuresis in a double-blind crossover trial"
09/01/1995 - "A prostaglandin synthesis inhibitor, diclofenac sodium in the treatment of primary nocturnal enuresis."
01/01/1992 - "The statistically significant difference in response to diclofenac sodium and to placebo leads us to use diclofenac sodium in primary nocturnal enuresis."
01/01/1992 - "The prostaglandin synthesis inhibitor diclofenac sodium was given as suppository in the treatment of primary nocturnal enuresis in 24 patients"
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09/01/1998 - "PURPOSE: Not all children with primary nocturnal enuresis, an unstable detrusor and small bladder capacity can be treated successfully with anticholinergics and bladder drill"
09/01/2005 - "The use of desmopressin, and anticholinergics in specific subgroups, was found to be effective and safe for the management of nocturnal enuresis in children."
01/01/2004 - "Current treatments for pediatric nocturnal enuresis rely upon the use of behavioral interventions, such as enuresis alarms, and pharmacological interventions, such as antidiuretic hormone analogs, tricyclic antidepressants, and anticholinergics"
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02/01/1997 - "CONCLUSIONS: Desmopressin tablets are an effective and safe alternative for treatment of nocturnal enuresis."
02/01/1994 - "A dose titration, and an open 6-week efficacy and safety study of desmopressin tablets in the management of nocturnal enuresis."
07/01/1987 - "A single blind dose response study of the effects of treatment with tablets containing 50-400 micrograms of desmopressin was conducted in 15 children with primary nocturnal enuresis"
03/01/2007 - "METHODS: If the parents and children consented to accept the treatment for 4 months and to keep on follow-up, the children diagnosed as primary nocturnal enuresis in the department of developmental and behavioral pediatrics in Shanghai Children's Medical Center from April 2003 to August 2004 were randomized into three groups: 52 children were in physio-psychological treatment group and were treated by utilizing the conditioning training role of alarm and other psychological and behavioral training programs; 46 children were in drug treatment group and were treated by taking DDAVP tablets orally; 40 children were in combined treatment group who were treated by applying the former two methods simultaneously"
12/01/1999 - "MATERIALS AND METHODS: We gave 33 children with monosymptomatic nocturnal enuresis resistant to the standard 0.4 mg. oral dose of desmopressin 0.4 and 0.8 mg. desmopressin and placebo tablets for 5 nights each in a double-blind crossover fashion"
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11/01/1987 - "Nocturnal enuresis was observed in 4 patients, 3 of whom responded favorably to I-desamino-8-D-arginine vasopressin therapy"
01/01/2007 - "MATERIAL AND METHODS: Measurements of urinary vasopressin and osmolality were made pre- and post-alarm treatment in a group (n=12) of outpatient children (aged 7-12 years) with severe (more than four times a week) nocturnal enuresis"
11/01/2006 - "Effect of 1-deamino 8-D-arginine vasopressin spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis."
05/11/2001 - "Intranasal administration of 1-deamino 8-D-arginine vasopressin (DDVAP) used for treatment of nocturnal enuresis (NE), might be expected to have various effects on the nasal mucosa, e.g"
08/01/2000 - "This paper proposes a model based on the notion that nocturnal enuresis arises through the ill functioning of one or more of the following three systems - a lack of vasopressin release during sleep; bladder instability; and/or an inability to arouse from sleep to bladder sensations"
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08/01/2006 - "CONCLUSIONS: The study suggests that an abnormally large nocturnal excretion of Na caused by selectively attenuated circadian rhythms of Na regulating hormones might be an important pathogenic factor in monosymptomatic nocturnal enuresis."
08/01/2006 - "PURPOSE: We investigated the circadian rhythm of solute excretion and regulating hormones as well as blood pressure in patients with monosymptomatic nocturnal enuresis"
10/01/2003 - "Although nocturnal enuresis has multiple causes, in recent years emphasis has focused on three main causes: lack of arousal, lack of antidiuretic hormone secretion and lack of bladder stability"
09/01/1997 - "Factors that have been observed to be associated with the occurrence of nocturnal enuresis include developmental delay, introduction of negative factors, heredity, small bladder capacity, and reduced nocturnal secretion of antidiuretic hormone"
04/01/1997 - "Indications for hormone treatment have since widened, especially as an effective solution for nocturnal enuresis"
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07/01/2001 - "Although tolterodine was ineffective in our patient to treat clozapine-induced nocturnal enuresis, further trials are required to appropriately evaluate the effectiveness of tolterodine to treat this adverse drug reaction."
01/01/2005 - "Twenty children with diurnal and nocturnal enuresis were given desmopressin and oxybutinine or desmopressin and tolterodine"
07/01/2001 - "DISCUSSION: This is the first published report of using tolterodine to treat clozapine-induced nocturnal enuresis"
07/01/2001 - "OBJECTIVE: To report the use and subsequent failure of the bladder-selective agent tolterodine, to treat clozapine-induced nocturnal enuresis in an adolescent patient with psychotic illness"
07/01/2001 - "Failure of tolterodine to treat clozapine-induced nocturnal enuresis."
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01/01/2006 - "CONCLUSIONS: Although the results of this study need to be confirmed in randomized, placebo-controlled trials, reboxetine may prove to be a useful treatment for therapy-resistant nocturnal enuresis."
01/01/2005 - "METHODS: Six children aged 12-15 years with primary nocturnal enuresis and with attention deficit/hyperactivity disorder with or without other comorbid disorders were treated with reboxetine (4-8 mg/day)"
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02/01/2006 - "Is a combination of alarm and drug therapies effective in nocturnal enuresis?"
01/01/2007 - "INTRODUCTION: We aimed at comparing the success rates of primary enuretic alarm therapy with those of secondary alarm therapy after failed pharmacotherapy in the treatment of monosymptomatic nocturnal enuresis (MNE)"
01/01/2007 - "Is second-line enuretic alarm therapy after unsuccessful pharmacotherapy superior to first-line therapy in the treatment of monosymptomatic nocturnal enuresis?"
08/01/2001 - "Combined pharmacotherapy for nocturnal enuresis."
09/01/1995 - "Various treatment modalities have been used in Primary Nocturnal Enuresis (PNE) and pharmacotherapy is widely accepted"
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06/01/1998 - "A previous retrospective study of 10 children with varying degrees of nocturnal enuresis has shown that one side effect of rapid maxillary expansion (RME) is spontaneous reduction in bed-wetting at night"
01/01/1990 - "In the ten cases examined in this study, nocturnal enuresis ceased within a few months of maxillary expansion."
03/01/2008 - "OBJECTIVE: To assess the effects of 10-14 days of rapid maxillary expansion (RME) on nocturnal enuresis (NE) in children who have long-standing resistance to medical therapy and to evaluate the long-term success rate after 10 years"
03/01/2008 - "Rapid maxillary expansion effects on nocturnal enuresis in children: a follow-up study."
10/01/2003 - "Effect of rapid maxillary expansion on nocturnal enuresis."
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07/01/2004 - "Laser acupuncture is a painless, non-invasive, and cost effective treatment for children with therapy resistant monosymptomatic nocturnal enuresis"
07/01/2004 - "Laser acupuncture as third-line therapy for primary nocturnal enuresis"
08/01/2001 - "CONCLUSION: Im comparison with pharmacological therapy using desmopressin, our study shows that laser acupuncture should be taken into account as an alternative, noninvasive, painless, cost-effective, and short-term therapy for children with primary nocturnal enuresis in case of a normal bladder function and high nighttime urine production"
08/01/2001 - "Prospective randomized trial using laser acupuncture versus desmopressin in the treatment of nocturnal enuresis."
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08/01/2008 - "This study examined the sustainability of remission of primary nocturnal enuresis (PNE) using an algorithm-based multimodal treatment plan, Try for Dry"
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06/01/2001 - "OBJECTIVES: To determine whether prompted voiding (PV) is effective for nighttime urinary incontinence in nursing home (NH) residents and whether residents who respond well to daytime PV also respond well at night"
04/01/1998 - "Nighttime urinary incontinence and sleep disruption among nursing home residents."
04/01/1993 - "OBJECTIVE: To describe the characteristics of nighttime urinary incontinence in a sample of nursing home (NH) residents"
01/01/2006 - "Oral ddAVP for nighttime urinary incontinence in characteriz