Fas-Associated Death Domain Protein (Fas-Associating Protein with Death Domain)

A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
Also Known As:
Fas-Associating Protein with Death Domain; FADD Protein, Fas-Associating; Fas Associated Death Domain Protein; Fas-Associating Protein FADD; MORT1 Protein; FADD Protein, Fas Associating; FADD, Fas-Associating Protein; Fas Associating Protein FADD; Fas Associating Protein with Death Domain; Fas-Associating FADD Protein
Networked: 39 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Yang, Xiao: 2 articles (01/2009 - 11/2007)
2. Al-Shabanah, Othman A: 1 article (01/2015)
3. Al Shrari, Shakir D: 1 article (01/2015)
4. Al-Harbi, Naif O: 1 article (01/2015)
5. Al-Hosaini, Khaled A: 1 article (01/2015)
6. Al Rejaie, Salim S: 1 article (01/2015)
7. Al-Hoshani, Ali Rashed: 1 article (01/2015)
8. Hafez, Mohamed M: 1 article (01/2015)
9. Sayed-Ahmed, Mohamed M: 1 article (01/2015)
10. Haralambieva, Eugenia: 1 article (09/2012)

Related Diseases

1. Sarcoma (Soft Tissue Sarcoma)
2. Neoplasms (Cancer)
3. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
4. Seizures (Seizure)
5. Hodgkin Disease (Hodgkin's Disease)

Related Drugs and Biologics

1. Protein Kinases (Protein Kinase)
2. Phosphotransferases (Kinase)
3. Interleukin-1beta (Interleukin 1 beta)
4. JNK Mitogen-Activated Protein Kinases
5. Caspase 8 (Caspase-8)
6. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
7. NF-kappa B (NF-kB)
8. Caspases
9. Ligands
10. Death Domain Receptors

Related Therapies and Procedures

1. Prostatectomy (Retropubic Prostatectomy)