|1.||Luo, Ting: 4 articles (09/2013 - 03/2009)|
|2.||Jiang, Yangfu: 4 articles (09/2013 - 03/2009)|
|3.||Bode, Ann M: 3 articles (11/2015 - 06/2011)|
|4.||Dong, Zigang: 3 articles (11/2015 - 06/2011)|
|5.||Kajo, Karol: 3 articles (04/2015 - 10/2014)|
|6.||Výbohová, Desanka: 3 articles (04/2015 - 10/2014)|
|7.||Kubatka, Peter: 3 articles (04/2015 - 10/2014)|
|8.||Péč, Martin: 3 articles (04/2015 - 10/2014)|
|9.||Kassayová, Monika: 3 articles (04/2015 - 10/2014)|
|10.||Stollárová, Nadežda: 3 articles (04/2015 - 10/2014)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2012 - "In the present study, we demonstrate that γ-T3 induces apoptosis in MDA-MB 231 and MCF-7 breast cancer cells as evident by PARP cleavage and caspase-7 activation. "
01/01/2015 - "Targeting survivin by YM155 modulated autophagy, induced autophagy-dependent caspase-7 activation and autophagy-dependent DNA damage in breast cancer cells. "
01/01/2013 - "The EEC treated MCF-7 cells also showed an increase in Bax/Bcl-2 ratio that in turn activated the caspase-dependent pathways by activating caspase 7. Thus, marine microalga, Chaetoceros calcitrans may be considered a good candidate to be developed as a new anti-breast cancer drug."
12/01/2009 - "Additional investigation showed that the mitochondrial damage was induced by the generation of ROS and the subsequent activation of caspase-7 and -9. Our findings demonstrate that VK(3)-induced apoptosis is selectively initiated by the mitochondria-related pathway and might be useful in breast cancer chemotherapy."
09/01/2013 - "HSP27 knockdown leads to an increase in Act D-induced caspase 3 and caspase 7 cleavage, and sensitizes rhabdosarcoma cells and breast cancer cells to Act D-induced apoptosis. "
|2.||Autistic Disorder (Autism)
01/01/2012 - "Alteration of the selected parameters confirm the role of neuroinflammation and apoptosis mechanisms in the etiology of autism together with the possibility of the use of HSP70, TGF-β2, Caspase 7 and INF-γ as predictive biomarkers that could be used to predict safety, efficacy of a specific suggested therapy or natural supplements, thereby providing guidance in selecting it for patients or tailoring its dose."
01/01/2012 - "This study aims to test the role that might be played by heat shock protein (HSP)70, transforming growth factor (TGF)-β2, Caspase 7 and interferon-γ (IFN-γ)in the pathophysiology of autism. "
11/01/2015 - "Caspase-7 is reportedly expressed at reduced levels in many cancers. "
08/27/2015 - "Potency of 22 was superior to 1 in MCF7 tumor spheroids and the mechanism of cell death was shown to be via apoptosis with an increase in cleaved PARP and activated caspase-7. "
01/01/2015 - "Polymorphisms in Caspase-7 (CASP7) may modulate the programmed cell death and thus contribute to cervical cancer risk. "
09/01/2013 - "Unshackling caspase-7 for cancer therapy."
01/01/2013 - "Caspase 7 (CASP7) is an important regulator and executioner in the apoptosis pathway and plays a crucial role in cancer development and progression. "
01/01/2013 - "Therefore, the goal of this study is to validate the UPR-induced caspase-7 as a new therapeutic target that modulates the UPR, reduces the level of apoptosis and protects the ADRP retina from retinal degeneration and light-induced damage. "
01/01/2014 - "The goal of this study is to validate whether reprogramming of the UPR via modulation of pro-apoptotic caspase-7 and CHOP proteins could be an effective approach to slow down the rate of retinal degeneration in ADRP mice. "
01/01/2013 - "Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration."
10/01/2008 - "To study the possible role of the caspase 7 (CASP7) gene in susceptibility to rheumatoid arthritis (RA) in a European Caucasian population. "
08/01/2007 - "The aim of this study was to investigate the possible role of the caspase 7 (CASP7) in susceptibility to rheumatoid arthritis (RA). "
08/01/2007 - "Caspase 7 influences susceptibility to rheumatoid arthritis."
|1.||Biological Markers (Surrogate Marker)
|2.||p38 Mitogen-Activated Protein Kinases
|4.||Caspase 3 (Caspase-3)
|6.||Proteins (Proteins, Gene)
|7.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|8.||Interleukin-8 (Interleukin 8)
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)
|3.||Prostatectomy (Retropubic Prostatectomy)
|4.||Photochemotherapy (Photodynamic Therapy)