Pyomyositis

An intramuscular suppuration of the large skeletal muscle groups. It is associated with INFECTION such as STAPHYLOCOCCUS AUREUS and PYODERMA. It was known as a tropical disease but is increasing among the immunocompromised (IMMUNOCOMPROMISED HOST). Symptoms include muscle pain, FEVER, and leucocytosis. It has been diagnosed by MRI SCANS.

Also Known As:

Networked: 190 relevant articles (8 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infections
2.	Abscess
3.	Pneumonia (Pneumonitis)
4.	Cellulitis
5.	Furunculosis (Boils)

Experts

1.	Yuen, Kwok-Yung: 2 articles (11/2010 - 02/2003)
2.	Chang, Feng-Yee: 2 articles (05/2009 - 08/2008)
3.	Chiu, Sheng-Kang: 2 articles (05/2009 - 08/2008)
4.	Koudela, K: 2 articles (06/2008 - 02/2005)
5.	Abd Algadir, Sami Ahmed: 1 article (04/2022)
6.	Abdelrahim Abdalla, Yassin: 1 article (04/2022)
7.	Claus, Filip: 1 article (04/2022)
8.	Demeyer, Ignace: 1 article (04/2022)
9.	Elsiddig Ahmed, Ali Ibrahim: 1 article (04/2022)
10.	Hamza, Salih Boushra: 1 article (04/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pyomyositis:

1.	Anti-Bacterial Agents (Antibiotics)IBA 05/20/2011 - "We present the first described case of iliopsoas pyomyositis with reversible bilateral hydroureteronephrosis that was treated successfully with intravenous antibiotics, without the necessity of surgical intervention. " 05/20/2011 - "This is the first case report describing iliopsoas pyomyositis with reversible bilateral dilation of the urinary tract that was treated successfully with intravenous antibiotics, without surgical intervention. " 02/27/2023 - "Patients were included as bacterial pyomyositis of the EOMs when there was a response to antibiotics alone or if a biopsy was consistent with the diagnosis. " 08/01/2021 - "A presumptive diagnosis of pyomyositis was made and the patient was treated with intravenous antibiotics with no improvement. " 07/01/2019 - "To treat the piriformis pyomyositis, broad-spectrum antibiotics were found to be useful; however, sometimes, antibiotic switching was warranted based on blood and tissue aspirate reports. "
2.	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 07/01/2023 - "After treatment with antibiotics for pyomyositis and ursodeoxycholic acid for PBC, the infection resolved in 8 weeks, and her glycemic control was improved after PBC treatment. "
3.	Insulin (Novolin)FDA Link 04/01/2022 - "The patient was diagnosed initially with diabetic ketoacidosis with pyomyositis and received analgesic and insulin; the patient partially improved. "
4.	AnticoagulantsIBA 01/01/2021 - "We describe the case of an 18-year-old male with pyomyositis of left piriform muscle, complicated with iliac and femoral vein thrombosis, that responded well to combined antibiotherapy, anticoagulants and drainage."
5.	Analgesics (Analgesic Drugs)IBA 04/01/2022 - "The patient was diagnosed initially with diabetic ketoacidosis with pyomyositis and received analgesic and insulin; the patient partially improved. "
6.	Ampicillin (Omnipen)FDA LinkGeneric 01/01/1983 - "The antibiotic was found to be effective in acute lobar pneumonia, pyogenic meningitis, acute and chronic bronchitis, acute pharyngitis, acute tonsillitis, cellulitis, furunculosis, and pyomyositis caused by such ampicillin-sensitive organisms as Neisseria meningitidis, Diplococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pyogenes, Klebsiella pneumoniae, and Escherichia coli. "
7.	CatalaseIBA 12/01/1992 - "Pyomyositis due to catalase-negative organism in patient with AIDS." 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
8.	Esculin (Aesculin)IBA 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
9.	Bacitracin (Baci-Rx)FDA LinkGeneric 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
10.	AgarIBA 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "

Therapies and Procedures

1.	Therapeutics 04/01/2023 - "Early diagnosis and appropriate antimicrobial therapy for pyomyositis are important, however, it is often missed in its early stage. " 01/01/2021 - "The findings in this case suggest that Escherichia coli should be considered when choosing initial empiric therapy for pyomyositis, especially in children with underlying conditions." 04/01/2013 - "This is the first report of TB pyomyositis in an infant; and highlights the need to have a high index of suspicion for unusual organisms when conventional therapy fails to demonstrate expected results. " 08/01/2011 - "coli should be considered for initial empiric therapy of pyomyositis in immunocompromised patients." 02/01/2010 - "The clinical history and management of severe disseminated pyomyositis, including diagnostic modalities, antimicrobial therapy, and surgical drainage, require an aggressive approach."
2.	Aftercare (After-Treatment) 07/01/2023 - "After treatment with antibiotics for pyomyositis and ursodeoxycholic acid for PBC, the infection resolved in 8 weeks, and her glycemic control was improved after PBC treatment. "
3.	Glycemic Control 07/01/2023 - "After treatment with antibiotics for pyomyositis and ursodeoxycholic acid for PBC, the infection resolved in 8 weeks, and her glycemic control was improved after PBC treatment. "
4.	Punctures 06/01/2008 - "Stage 2 pyomyositis needs surgical intervention with abscess aspiration and drainage; in some cases CT-guided needle puncture with pigtail drain insertion is sufficient. " 07/01/1996 - "Diagnosis was established using needle puncture and histological (lymphoma) and bacteriological (pyomyositis) examination. " 06/01/2000 - "Also discussed are contiguous osteomyelitis with and without vascular insufficiency, puncture wound osteomyelitis, vertebral osteomyelitis, osteomyelitis with sickle cell disease, chronic osteomyelitis, pyomyositis, acute bacterial myositis, and nonstreptococcal myonecrosis." 01/01/2016 - "Seventeen patients received surgical treatment, aspirative punctures, 9; antibiotics alone, 4. Twenty eight (93.3%) patients had a good evolution; deaths, 2 (6.6%); unknown, 2. Main conclusions of this study were: due to the diverse and changing etiology of the primary pyomyositis it is important to recognize the etiological agent involved and their antibiotic susceptibility. " 02/01/2005 - "The therapy of pyomyositis must be initiated in time by bed rest and administration of antibiotics and, if an abscess develops, surgical intervention is unconditionally necessary, consisting either in percutaneous abscess puncture or incision, perfusion, and application of antibiotics. "
5.	Drug Therapy (Chemotherapy) 10/01/2010 - "Pyomyositis is a rare complication of chemotherapy that is commonly seen in tropical climates and in patients with immunodeficiency states. " 07/01/2003 - "Pyomyositis is a rare complication of chemotherapy. " 02/01/2000 - "Pyomyositis is a rare complication of chemotherapy. " 06/01/1994 - "Successful percutaneous drainage of gluteal pyomyositis occurring after intra-arterial chemotherapy and pelvic irradiation." 05/01/2021 - "Pyomyositis in a Patient Undergoing Chemotherapy for Gastric Cancer: A Case Report and Literature Review."