HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Fanconi Anemia Complementation Group D2 Protein

A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
Also Known As:
FANCD2 Protein; Fanconi Anemia Group D2 Complementing Protein; Fanconi Anemia Group D2 Protein
Networked: 25 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. van Diest, Paul J: 3 articles (01/2008 - 10/2003)
2. de Winter, Johan P: 3 articles (01/2008 - 10/2003)
3. D'Andrea, Alan D: 3 articles (08/2006 - 12/2002)
4. Wilson, James B: 2 articles (06/2010 - 11/2009)
5. Jones, Nigel J: 2 articles (06/2010 - 11/2009)
6. Kupfer, Gary M: 2 articles (11/2009 - 08/2006)
7. Grompe, M: 2 articles (01/2009 - 02/2001)
8. Hejna, J: 2 articles (01/2009 - 02/2001)
9. Patel, Ketan J: 2 articles (12/2008 - 07/2003)
10. Joenje, Hans: 2 articles (01/2008 - 10/2003)

Related Diseases

1. Fanconi Anemia (Fanconi's Anemia)
2. Neoplasms (Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Genomic Instability
5. Ovarian Neoplasms (Ovarian Cancer)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. Proteins (Proteins, Gene)
3. Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
4. Ubiquitin
5. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6. Serine (L-Serine)
7. Platinum
8. Paraffin
9. Formaldehyde (Formol)
10. Curcumin

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)