Fanconi Anemia Complementation Group F Protein

A Fanconi anemia complementation group protein. It is an essential component of a nuclear core complex that protects the GENOME against CHROMOSOMAL INSTABILITY. It interacts directly with FANCG PROTEIN and helps stabilize a complex with FANCA PROTEIN and FANCC PROTEIN.

Also Known As:

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Duan, Shiwei: 1 article (01/2020)
2.	Gao, Tong: 1 article (01/2020)
3.	Pan, Ranran: 1 article (01/2020)
4.	Wu, Dongping: 1 article (01/2020)
5.	Ying, Jieer: 1 article (01/2020)
6.	Yu, Hang: 1 article (01/2020)
7.	Bai, Xuefeng: 1 article (07/2014)
8.	He, Miao: 1 article (07/2014)
9.	Li, Yanlin: 1 article (07/2014)
10.	Lin, Shu: 1 article (07/2014)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "Fanconi anemia complement group F (FANCF) is known to be involved in DNA repair, and the overexpression of FANCF protein leads to cell proliferation and ultimately to cancer. " 07/01/2014 - "In the present study, we investigated the effect of Fanconi anemia complementation group F protein (FANCF), a critical factor of the FA/BRCA pathway, on cancer cell apoptosis induced by DNA alkylating agents such as mitomycin c (MMC). "
2.	Ovarian Neoplasms (Ovarian Cancer) 03/01/2006 - "Similarly, the level of FANCF protein decreased in ovarian cancers. "
3.	Fanconi Anemia (Fanconi's Anemia) 01/01/2020 - "Fanconi anemia complement group F (FANCF) is known to be involved in DNA repair, and the overexpression of FANCF protein leads to cell proliferation and ultimately to cancer. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Alkylating Agents
3.	Complement System Proteins (Complement)