|3.||Renal Cell Carcinoma (Grawitz Tumor)
|4.||Autosomal Dominant Polycystic Kidney (ADPKD)
|5.||Chronic Kidney Failure (Chronic Renal Failure)
|1.||Hildebrandt, Friedhelm: 10 articles (02/2011 - 10/2002)|
|2.||Antignac, Corinne: 7 articles (10/2015 - 07/2003)|
|3.||Attanasio, Massimo: 5 articles (10/2015 - 01/2009)|
|4.||Bleyer, Anthony J: 5 articles (10/2015 - 08/2003)|
|5.||Yoder, Bradley K: 5 articles (08/2011 - 03/2002)|
|6.||Horácek, J: 5 articles (12/2008 - 03/2004)|
|7.||Gregor, V: 5 articles (12/2008 - 03/2004)|
|8.||Sípek, A: 5 articles (12/2008 - 03/2004)|
|9.||Beier, David R: 4 articles (01/2015 - 12/2002)|
|10.||Zhou, Weibin: 4 articles (01/2014 - 06/2007)|
|1.||Proteins (Proteins, Gene)IBA
06/01/2007 - "Positional cloning of six novel genes (NPHP1 through 6) as mutated in NPHP and functional characterization of their encoded proteins have contributed to the concept of "ciliopathies." It has helped advance a new unifying theory of cystic kidney diseases. "
01/01/2012 - "This study establishes the LPK rat as a novel model system for NPHP and further consolidates the link between cystic kidney disease and cilia proteins."
05/01/2011 - "Studies of the primary cilium, now known to be present in all cells, have undergone a revolution, in part, because mutation of many of its proteins causes a large number of diseases, including cystic kidney disease. "
07/01/2015 - "Several ciliopathy proteins that contribute to the pathogenesis of cystic kidney diseases and ciliopathy-related phenotypes have been recently reported to participate in the elaborated pathways that control DNA replication and repair, suggesting that malfunction of these biological processes may be a common denominator of some ciliopathy-related diseases. "
04/01/2015 - "Almost all of proteins associated with a broad spectrum of human cystic kidney diseases have been localized to the region in or around the cilia. "
|2.||Hereditary renal agenesisIBA
09/01/2013 - "Increase in postnatally diagnosed cases can be attributed primarily to the reporting of less severe cases (cystic kidney disease) or unilateral anomalies (renal agenesis and hypoplasia). "
03/01/2004 - "In cases of birth cystic kidney 25% were diagnosed prenatally and ended for renal agenesis and hypoplasie of the kidneys and 27% due to cystic kidney. "
08/01/2015 - "Prenatal renal diagnoses were as follows: hydronephrosis/megaureter: n = 21 (20.2 %), aberrance in renal form or location: n = 7 (6.7 %), cystic renal disease: n = 28 (26.9 %), renal dysplasia: n = 24 (23.1 %), renal agenesis: n = 42 (30.4 %), posterior urethral valves: n = 11 (10.6 %). "
09/01/2013 - "The overall prevalence rates of the monitored diagnoses from the group of congenital kidney disease (cystic kidney disease and renal agenesis/hypoplasia) were on the rise in the monitored -period mainly due to advances in imaging technologies (ultrasonography) and their use in both prenatal and postnatal diagnosis. "
06/01/2012 - "Fraser syndrome (FS) features renal agenesis and cystic kidneys. "
|3.||Messenger RNA (mRNA)IBA
02/01/1992 - "Previous studies had shown higher steady-state levels of proto-oncogene mRNA in these cystic kidneys. "
11/01/2002 - "Messenger RNA expression in multiple affected organs was analyzed to determine if common gene cascades were misexpressed in the cystic kidney and extrarenal sites of disease. "
02/01/1996 - "At all time points studied, cystic kidneys exhibited increased expression of c-myc mRNA as compared with phenotypic normal kidneys, consistent with PKD being a hyperplastic disease of renal tubules. "
02/01/1992 - "c-myc mRNA was detected by in situ hybridization in nephron anlagen and elongating tubules of normal and cystic kidneys during late fetal and early neonatal kidney development. "
02/01/1992 - "It is now shown using nuclear run-on transcription that the c-fos and c-myc proto-oncogenes are transcribed at higher rates in cystic kidneys, and thus that increased transcription, in part, may account for the increased mRNA levels. "
07/01/1976 - "The results of this study show that, in the terminal stages, cellular as well as gross morphologic differences exist between polycystic and medullary cystic kidney disease and that diphenylamine-induced cystic disease more closely resembles human polycystic than medullary cystic kidney disease."
07/01/1976 - "Most prominent among them is the renal cystic disease that is induced in rats through feeding of the antioxidant, diphenylamine, The present study examined the morphology of adult polycystic and medullary cystic kidney disease in man using scanning electron microscopy and compared them with diphenylamine-induced cystic kidney disease in rats. "
11/01/1987 - "[Cystic kidney disease induced by diphenylamine in rats]."
01/01/1978 - "Chronic intoxication with diphenylamine (DPA), which causes a cystic kidney disease in the rat and the guinea-pig, caused degeneration of the renal tubular epithelium in the chicken. "
07/01/1976 - "Comparison of human polycystic and medullary cystic kidney disease with diphenylamine-induced cystic disease."
10/09/2015 - "These studies reveal a novel pathway whereby HNF-1β directly contributes to the control of miRNAs that are involved in epithelial-mesenchymal transition and cystic kidney disease. "
04/01/2015 - "There is increasing evidence that microRNA (miRNA) dysregulation is associated with the pathogenesis of cystic kidney disease. "
04/01/2015 - "MicroRNAs in the pathogenesis of cystic kidney disease."
07/01/2009 - "Specific miRNAs have been implicated in pathways linked to cystic kidney disease (miR-15a), and Wilms' tumor (miR-17-92). "
04/01/2015 - "The relationship of specific miRNAs, such as the miR-17∼92 cluster and cystic kidney disease, miR-92a and von Hippel-Lindau syndrome, and alterations in LIN28-LET7 expression in Wilms tumor will be explored. "
|6.||Proliferating Cell Nuclear Antigen (PCNA)IBA
04/01/1998 - "Image analysis of proliferating cell nuclear antigen expression and immunohistochemical profiles in renal cell carcinoma associated with acquired cystic kidney disease: comparison with classic renal cell carcinoma."
01/01/1995 - "In this study, which used immunohistochemical methods with an antibody to proliferating cell nuclear antigen (PCNA), the proliferation index (PI) (percentage of PCNA positive cell nuclei among epithelial cells lining the renal cysts) was determined in 10 cases of autosomal dominant polycystic kidney disease (ADPKD), 8 cases of autosomal recessive polycystic kidney disease (ARPKD), and 8 cases of acquired cystic kidney disease (ACKD). "
01/01/1997 - "We report the immunohistochemical (cytokeratin, epithelial membrane antigen, vimentin, Tamm-Horsfall protein, proliferating cell nuclear antigen) and lectin-binding (soybean agglutinin, Dolichos biflorus agglutinin) profile of cystic kidneys from 9 surgically removed and 21 autopsy cases. "
02/01/2012 - "Activation of the renin system, as supported by recent studies, can explain the mechanism of hypokalemia and hypertension in this inherited cystic kidney disorder. "
12/01/2010 - "Intrarenal renin, ACE and Ang II expression was increased significantly in cystic kidneys; angiotensinogen and Ang II Type I receptor were unchanged. "
01/12/2001 - "Human RHBG resides at chromosome 1q21.3, which harbors candidate genes for medullary cystic kidney disease, whereas mouse Rhbg is syntenic on chromosome 3. Northern blot and in situ hybridization revealed that RHBG and Rhbg are predominantly expressed in liver, kidney, and skin, the specialized organs involving ammonia genesis, excretion, or secretion. "
11/01/2000 - "The present study tested whether this beneficial effect is sustained and explored handling of citrate and ammonia in normal and cystic kidneys. "
|9.||Neural tube defects X-linkedIBA
12/01/2008 - "Total numbers and mean incidences of selected types of defects (anencephaly, spina bifida, encephalocele, congenital hydrocefalus, omfalocele, gastroschisis, diafragmatic hernia, cystic kidney, renal agenesis/hypoplasia, transposition of great vessels, tetralogy of Fallot, hypoplastic left heart syndrome and coarctation of aorta) during the period under the study were analyzed. "
12/01/2008 - "Mean incidences of selected types of defects (anencephaly, spina bifida, encephalocele, total neural tube defects, congenital hydrocephalus, omfalocele, gastroschisis, total abdominal wall defects, diaphragmatic hernia, renal agenesis/hypoplasia, cystic kidney, Down syndrome and others) in 2006 were analyzed. "
|10.||Citric Acid (Citrate)FDA LinkGeneric
02/01/2004 - "In the case of marked bilateral cystic kidneys, a bilateral retroperitoneoscopic adrenalectomy in Cushing's syndrome is technical possible and a safe and effective method of treatment."
07/01/2006 - "This patient underwent right adrenalectomy and nephrectomy in consideration of future generation of cancer in the acquired cystic kidney. "
|3.||Renal Dialysis (Hemodialysis)
06/01/1991 - "[Acquired cystic kidney disease among hemodialysis patients: echographic and clinical study]."
04/27/1991 - "To evaluate the usefulness of echography for the evaluation of these lesions and the prevalence of acquired cystic renal disease and occult renal tumours in patients treated with hemodialysis during years, a prospective ultrasonographic study was carried out. "
10/01/2015 - "We presented 3 patients undergoing hemodialysis, with acquired cystic kidney disease accompanied by the development of RCC. "
07/01/2015 - "Acquired cystic kidney disease (ACKD) may cause SRH in hemodialysis patients. "
04/01/2013 - "Acquired cystic kidney disease is a common finding in chronic hemodialysis patients. "
|4.||Transplantation (Transplant Recipients)
11/01/2013 - "Pilot study of non-contrast-enhanced MRI vs. ultrasound in renal transplant recipients with acquired cystic kidney disease: a prospective intra-individual comparison."
10/01/2012 - "The imaging recommendations and supportive data are intended to ease the physicians' difficult task of dealing with the specific diagnostic demands of paediatric paediatric cystic kidney disease and transplantation."
09/01/2012 - "Contrast-enhanced ultrasound assessment of complex cystic lesions in renal transplant recipients with acquired cystic kidney disease: preliminary experience."
04/01/2012 - "Acquired cystic kidney disease (ACKD) was found more frequently in the dialysis group, and it had a statistically relevant effect on the occurrence of RCC by comparison with the transplantation group (p<0.01). "
04/01/1998 - "To evaluate the impact of magnetic resonance imaging (MRI) in renal transplant recipients whose ultrasound (US) examinations of the native kidneys have met the criteria of acquired cystic kidney disease (ACKD). "
01/01/1992 - "Renal malignancy in peritoneal dialysis patients with acquired cystic kidney disease."
02/01/1988 - "Acquired cystic kidney disease: occurrence in patients on chronic peritoneal dialysis."
03/01/2009 - "Over time, there was an increase in the percentage of young adults who started RRT at a very young age, a greater number of children with hypoplasia/dysplasia and cystic kidneys and more young adults who started RRT with peritoneal dialysis or pre-emptive transplantation. "
03/01/2002 - "Dialysis-associated acquired cystic kidney disease imitating autosomal dominant polycystic kidney disease in a patient receiving long-term peritoneal dialysis."
02/01/2002 - "We describe here the clinicopathological findings in a child with congenital nephrotic syndrome (CNS) non-responsive to medical therapy who developed acquired cystic kidney disease (ACKD) in both native kidneys after long-term peritoneal dialysis. "