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Centromere Protein B

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A DNA-binding protein that interacts with a 17-base pair sequence known as the CENP-B box motif. The protein is localized constitutively to the CENTROMERE and plays an important role in its maintenance.

Also Known As:

CENP-B Protein; Centromere Autoantigen 80K; CENP B Protein

Networked: 5 relevant articles (0 outcomes, 1 trials/studies) for this Bio-Agent, Comments

Bio-Agent Context: Research Results

Experts

1.	Miranda-Filloy, Jose A: 1 article (05/2008)
2.	Llorca, Javier: 1 article (05/2008)
3.	Gonzalez-Juanatey, Carlos: 1 article (05/2008)
4.	Gonzalez-Gay, Miguel A: 1 article (05/2008)
5.	Arias-Nuñez, Maria C: 1 article (05/2008)
6.	Amor-Dorado, Juan C: 1 article (05/2008)

Related Diseases

1.	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 07/01/1995 - "The purpose of the present study is to evaluate the centromeric pattern on human laryngeal tumour (HEp-2) cells by indirect immunofluorescent (IIF) test and to compare their reactivities with a newly developed recombinant centromere protein B enzyme linked immunosorbent assay (CENP-B ELISA) test using sera of antinuclear antibody (ANA)-reactive primary biliary cirrhosis (PBC) patients. " Order ALL the reference details at left...
2.	Autoimmune Diseases (Autoimmune Disease) 02/01/1992 - "The purified protein was identified as the centromere protein B (CENP-B) by its mobility on SDS-PAGE (80 kD), and reactivities to a monoclonal antibody raised to CENP-B (bacterial fusion protein) and to anticentromere sera from patients with autoimmune diseases. " 10/01/1992 - "Centromere protein B (CENP-B), which is an alphoid DNA binding protein, is the target antigen in autoimmune disease patients (often with scleroderma). " 01/01/1992 - "Centromere protein B (CENP-B), which is an alphoid DNA binding protein, is the target antigen in autoimmune disease patients (often those with scleroderma). " Order ALL the reference details at left...
3.	Systemic Scleroderma (Systemic Sclerosis) 05/01/2008 - "Audiovestibular manifestations in patients with limited systemic sclerosis and centromere protein-B (CENP-B) antibodies." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antinuclear Antibodies
2.	DNA-Binding Proteins (DNA Binding Protein)
3.	Antigens
4.	Antibodies

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