CD79 Antigens

Components of the B-cell antigen receptor that function in B-cell antigen receptor heavy chain transport to the PLASMA MEMBRANE. They are expressed almost exclusively by B-LYMPHOCYTES and are markers for B-cell NEOPLASMS.

Also Known As:

B-Cell Antigen Receptor Complex Associated Protein Beta-Chain; CD79 Antigen; CD79a Antigen; CD79b Antigen; IgM-Alpha Component; Igbeta Antigen; Immunoglobulin-Associated Alpha Protein; Immunoglobulin-Associated Beta Protein; Antigen, CD79; Antigen, CD79a; Antigen, CD79b; Antigen, Igbeta; B Cell Antigen Receptor Complex Associated Protein Beta Chain; IgM Alpha Component; Immunoglobulin Associated Alpha Protein; Immunoglobulin Associated Beta Protein; Antigens, CD79; Antigens, CD79a; Antigens, CD79b; CD79a Antigens; CD79b Antigens

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Arroyo, Luis G: 1 article (01/2018)
2.	Bienzle, Dorothee: 1 article (01/2018)
3.	Cooper, Carina J: 1 article (01/2018)
4.	Hewson, Joanne: 1 article (01/2018)
5.	Keller, Stefan M: 1 article (01/2018)
6.	Kenney, Daniel: 1 article (01/2018)
7.	Bailey, Denis: 1 article (07/2013)
8.	Boerner, Scott L: 1 article (07/2013)
9.	Crump, Michael: 1 article (07/2013)
10.	Geddie, William R: 1 article (07/2013)

Related Diseases

1.	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/01/2022 - "Previous studies have shown that diffuse large B-cell lymphoma (DLBCL) subtype with both B-cell antigen receptor complex-associated protein beta chain (CD79B) and myeloid differentiation primary response 88 mutations (MYD88) had inferior outcome under standard immunochemotherapy. "
2.	Sclerosis 07/01/1997 - "In this study we analyzed 96 sequential biopsy specimens (>1 month apart) obtained from 44 patients (nodular sclerosis, 34 specimens; mixed cellularity, 5; lymphocyte depletion, 1; unclassified, 4) using fixed, paraffin-embedded sections; heat-induced epitope retrieval (HIER); a panel of antibodies specific for the CD3, CD15, CD20, CD30, CD43, CD45/45RB, and CD79a antigens and Epstein-Barr virus latent-membrane protein; and a streptavidin-biotin method. "
3.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/01/2018 - "Six cases were classified as acute lymphocytic leukemia (ALL) based on predominance of blasts, lack of granulocytic or monocytic differentiation, and detection of CD3, CD20, and/or CD79a antigens by immunohistochemistry. " 01/01/2001 - "A diagnosis of high-grade lymphoblastic lymphoma was made by histological evaluation of fixed lymph node biopsy sections, whilst immunohistochemical analyses demonstrated co-expression of B- and T-cell antigens (CD79a and CD3) by 95% of lymphomatous cells. "
4.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/01/2005 - "Aberrant expression of CD7, CD56, and CD79a antigens in acute myeloid leukemias."
5.	Paraproteinemias (Monoclonal Gammopathy) 04/01/2003 - "Differential diagnosis is based on: (1) clinical and laboratory features (anemia, organomegaly, lymphadenopathy, IgM paraproteinemia), (2) cell morphology (lymphocytes, lymphoplasmacytes, few plasma cells), (3) histopathology of bone marrow or lymph node, (4) immunophenotype (CD5 expression and the intensity of CD5, CD20, and CD79b antigens may help in discrimination from other LPDs and atypical CLL), and (5) characteristic genetic features (present in other LPDs). "

Related Drugs and Biologics

1.	Streptavidin
2.	Paraffin
3.	Membrane Proteins (Integral Membrane Proteins)
4.	Biotin (Vitamin H)
5.	Epitopes
6.	Antibodies
7.	Immunoglobulin M (IgM)
8.	Enhancer of Zeste Homolog 2 Protein