|1.||ten Dijke, Peter: 2 articles (04/2013 - 02/2003)|
|2.||Liu, Fu-You: 2 articles (01/2007 - 01/2006)|
|3.||Li, Xiao-Zhao: 2 articles (01/2007 - 01/2006)|
|4.||Zhang, Da-Dong: 1 article (04/2014)|
|5.||Chen, Sha-Sha: 1 article (04/2014)|
|6.||Cong, Xin-Peng: 1 article (04/2014)|
|7.||Hou, Shi-Qiang: 1 article (04/2014)|
|8.||Li, Xin-Ming: 1 article (04/2014)|
|9.||Fang, Ming: 1 article (04/2014)|
|10.||Zheng, Jun: 1 article (10/2013)|
01/01/2006 - "Studies indicate that the level of Smad7 protein expression is decreased in progression of tubulointerstitial fibrosis. "
09/01/2010 - "Trps1 haploinsufficiency promoted tubulointerstitial fibrosis via increased phosphorylation of Smad3 and decreased Smad7 protein. "
06/08/2004 - "Our results suggest that the reduction of Smad7 protein resulting from enhanced ubiquitin-dependent degradation plays a pathogenic role in progression of tubulointerstitial fibrosis."
04/01/2004 - "Additionally, inhibition of Smad3 by overexpression of the inhibitory Smad7 protein or by treatment with the small molecule, halofuginone, dramatically reduces responses in animal models of kidney, lung, liver and radiation-induced fibrosis. "
06/08/2004 - "Compared with sham-operated kidneys, the level of Smad7 protein, but not mRNA, decreased progressively in UUO kidneys, whereas immunoreactivity for nuclear phosphorylated Smad2 and Smad3 and renal fibrosis were inversely increased. "
04/01/2013 - "At 12 weeks post-infection, the level of Smad7 protein was higher [(6.34 +/- 1.5)%], but with prolonged infection time, no significant difference was revealed (P > 0.05). "
04/01/2013 - "After 8 weeks post infection, Smad7 protein sparsely appeared around the granuloma [(4.15 +/- 1.26)%] while it disappeared around liver sinus. "
02/01/2003 - "Infection of hGL cells with Ad-Smad7, which expresses the inhibitory Smad7 protein, suppressed the levels of both GDF-9-induced endogenous and adenoviral alpha PS2-reactive proteins. "
01/01/2007 - "The results indicated progressive tubulointerstitial fibrosis, high expression levels of Arkadia, Smurf2, TbetaRI, TGF-beta1 mRNA, type 1 collagen mRNA, and Smad7 mRNA, and low levels of Smad7 protein in the kidneys of rats with unilateral ureteral obstruction, in which Smurf2 interacted with both Smad7 and TbetaRI, and Arkadia only interacted with Samd7 but not with TbetaRI. "
|1.||Transforming Growth Factor beta1 (TGF beta 1)
|2.||Messenger RNA (mRNA)
|4.||Collagen Type I (Type I Collagen)
|6.||Transforming Growth Factor beta (TGF-beta)
|7.||Proteins (Proteins, Gene)
|10.||salicylhydroxamic acid (SHAM)