HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Smad4 Protein

A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.
Also Known As:
Common Smad; MADH4 Protein; Smad, Common
Networked: 65 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Cao, Xu: 4 articles (09/2006 - 05/2005)
2. Wan, Mei: 3 articles (09/2006 - 05/2005)
3. Tang, Yi: 3 articles (09/2006 - 05/2005)
4. Wang, Ning: 3 articles (09/2006 - 05/2005)
5. Davison, Jon M: 2 articles (04/2015 - 05/2014)
6. Singhi, Aatur D: 2 articles (04/2015 - 05/2014)
7. Iacobuzio-Donahue, Christine A: 2 articles (11/2012 - 03/2004)
8. Hruban, Ralph H: 2 articles (11/2012 - 03/2004)
9. Hao, Jun: 2 articles (03/2011 - 01/2011)
10. Zhou, Yingqi: 2 articles (03/2011 - 01/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Anoxia (Hypoxia)
4. Neoplasm Metastasis (Metastasis)
5. Pancreatic Neoplasms (Pancreatic Cancer)

Related Drugs and Biologics

1. Messenger RNA (mRNA)
2. Transforming Growth Factor beta (TGF-beta)
3. Transforming Growth Factor beta1 (TGF beta 1)
4. Ubiquitin
5. Proteins (Proteins, Gene)
6. Transforming Growth Factor beta2
7. Smad Proteins (Mothers Against Decapentaplegic Homolog)
8. Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
9. Small Interfering RNA (siRNA)
10. Collagen Type I (Type I Collagen)

Related Therapies and Procedures

1. Pancreaticoduodenectomy