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Notch Receptors

A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.
Also Known As:
Receptors, Notch; Notch Proteins
Networked: 156 relevant articles (2 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Han, Hua: 5 articles (12/2015 - 01/2008)
2. Miele, Lucio: 5 articles (10/2011 - 11/2005)
3. Liang, Liang: 4 articles (12/2015 - 01/2008)
4. Blacklow, Stephen C: 4 articles (10/2011 - 02/2007)
5. Aster, Jon C: 4 articles (10/2011 - 02/2007)
6. Zheng, Min-Hua: 3 articles (12/2015 - 09/2013)
7. Egan, Sean E: 3 articles (10/2014 - 09/2005)
8. Masiero, Massimo: 3 articles (01/2014 - 02/2009)
9. Farnie, Gillian: 3 articles (01/2013 - 06/2007)
10. Clarke, Robert B: 3 articles (01/2013 - 06/2007)

Related Diseases

1. Inflammation
2. Kidney Diseases (Kidney Disease)
3. Cicatrix (Scar)
4. Neoplasms (Cancer)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Transcription Factors (Transcription Factor)
2. Blocking Antibodies
3. Ligands
4. Proteins (Proteins, Gene)
5. Messenger RNA (mRNA)
6. Transposases
7. CD44 Antigens
8. Carrier Proteins (Binding Protein)
9. Amyloid Precursor Protein Secretases (beta-Secretase)
10. Presenilins