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Replication Protein C (Replication Factor C)

A DNA-binding protein that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Also Known As:
Replication Factor C; Activator 1 Protein; Activator 1 Protein, 145 kDa Subunit; Activator 1 Protein, 36 kDa Subunit; Activator 1 Protein, 37 kDa Subunit; Activator 1 Protein, 38 kDa Subunit; Activator 1 Protein, 40 kDa Subunit; Activator 1 p40; Replication Factor C, Subunit 1; Replication Factor C, Subunit 2; Replication Factor C, Subunit 3; Replication Factor C, Subunit 4; Replication Factor C, Subunit 5; Replication Protein C, Subunit 1; Replication Protein C, Subunit 2; Replication Protein C, Subunit 3; Replication Protein C, Subunit 4; Replication Protein C, Subunit 5
Networked: 19 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Kubota, Takashi: 2 articles (08/2013 - 07/2011)
2. Donaldson, Anne D: 2 articles (08/2013 - 07/2011)
3. Myung, Kyungjae: 2 articles (08/2013 - 04/2010)
4. Kupiec, Martin: 2 articles (04/2005 - 08/2003)
5. Nishitani, Hideo: 1 article (11/2013)
6. Shiomi, Yasushi: 1 article (11/2013)
7. Lamond, Angus I: 1 article (07/2011)
8. Yamada, Kayo: 1 article (07/2011)
9. Hiraga, Shin-ichiro: 1 article (07/2011)
10. D'Andrea, Alan D: 1 article (04/2010)

Related Diseases

1. Genomic Instability
2. Neoplasms (Cancer)
3. Chromosomal Instability (Chromosome Stability)
4. Williams Syndrome (Williams-Beuren Syndrome)
5. Xeroderma Pigmentosum (Kaposi's Disease)

Related Drugs and Biologics

1. Proliferating Cell Nuclear Antigen (PCNA)
2. DNA (Deoxyribonucleic Acid)
3. Replication Protein A
4. DNA Primase (Primase)
5. DNA Polymerase III (Pol III)
6. Tumor Viral Antigens (Large T Antigen)
7. DNA Topoisomerases
8. Transcription Factors (Transcription Factor)
9. Proteins (Proteins, Gene)
10. Chromatin