|1.||Semenza, Gregg L: 55 articles (11/2015 - 01/2002)|
|2.||Hirota, Kiichi: 12 articles (01/2015 - 10/2002)|
|3.||Brüne, Bernhard: 12 articles (09/2014 - 04/2004)|
|4.||Harris, Adrian L: 10 articles (12/2015 - 01/2004)|
|5.||Harada, Hiroshi: 10 articles (01/2015 - 09/2008)|
|6.||Simos, George: 8 articles (04/2013 - 08/2006)|
|7.||Fandrey, Joachim: 8 articles (06/2012 - 09/2004)|
|8.||Zhou, Jie: 8 articles (09/2009 - 04/2004)|
|9.||Gilkes, Daniele M: 7 articles (11/2015 - 09/2011)|
|10.||Hiraoka, Masahiro: 7 articles (01/2015 - 09/2008)|
06/01/2008 - "To enhance the efficacy of cancer treatment, we propose a complex approach: simultaneous delivery to the tumor of a chemotherapeutic agent and a suppressor of hypoxia-inducible factor 1 alpha (HIF1A). "
01/01/2014 - "The results from the published studies on the association between hypoxia-inducible factor-1(Hif-1/HIF-1) polymorphisms and cancer risk are conflicting. "
11/01/2015 - "Furthermore, low doses of LMP-400 decreased the protein levels of hypoxia-inducible factor 1 (HIF-1α), one of a family of factors studied as potential metastatic drivers in these tumors. "
01/28/2015 - "Moreover, the antitumor activity of LCL-SIM depends on the presence of functional tumor-associated macrophages (TAM) in tumor tissue and is mainly based on the reduction of the TAM-mediated oxidative stress as well as of the production of the hypoxia-inducible factor 1 α (HIF-1 α) in tumors. "
07/01/2014 - "Microvascular density (MVD), Ki67 tumor cell proliferation index and hypoxia-inducible factor 1 alpha (HIF-1 alpha) index were determined by immunohistochemistry. "
03/01/2010 - "Expression of hypoxia-inducible factor 1 alpha in thyroid carcinomas."
05/01/2008 - "To observe the influence of hypoxia-inducible factor 1 alpha (HIF-1alpha) on angiogenesis in prostate carcinoma in vivo and to investigate its molecular mechanism. "
08/01/2007 - "Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma."
03/01/2003 - "Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1."
02/25/2002 - "Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma."
01/01/2014 - "Hypoxia-inducible factor 1 alpha contributes to pulmonary vascular dysfunction in lung ischemia-reperfusion injury."
06/20/2011 - "The aim of this study was to investigate whether isoflurane preconditioning provides a protection against renal ischemic-reperfusion injury and whether hypoxia inducible factor 1 α (HIF-1 α) is responsible for the protection afforded by isoflurane in mice. "
04/01/2010 - "[Isoflurane produces delayed preconditioning against renal ischemia/reperfusion injury via hypoxia inducible factor 1 alpha activation]."
11/01/2008 - "Expression of hypoxia-inducible factor 1 alpha regulated genes was not influenced by cardioplegia and reperfusion, ischemic preconditioning or unstable angina. "
11/01/2008 - "We hypothesized that preceding unstable angina and/or ischemic preconditioning activated genes regulated by nuclear factor kappa B (NFkappaB) or hypoxia-inducible factor 1 alpha in parallel to improved cardiac function. "
11/01/2008 - "Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart."
12/15/2012 - "The aim of this study was to test the effect of hypoxia and its master transcriptional regulator hypoxia-inducible factor 1 (HIF-1) on S100A8/A9 expression. "
12/01/2012 - "The study objective was to investigate the role of hypoxia-inducible factor 1 (HIF-1) in the transcriptional activation of MUC5AC in human bronchial epithelial (HBE) 16 cells under hypoxia conditions and the effect of hypoxia on expression and secretion of MUC5AC. "
12/01/2009 - "The purpose of this study was to construct a novel mutant TKGFP fusion reporter gene with low cytotoxicity and high temporal resolution for use in the real-time monitoring of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor 1 (HIF-1) signal transduction activity mediated by hypoxia and reoxygenation in vitro and in vivo. "
11/01/2006 - "In this study, we specifically investigated the role of hypoxia inducible factor 1 alpha (HIF-1alpha) in the hepatocellular response to hypoxia. "
11/01/2006 - "In this study we tested the hypothesis that hypoxia-induced changes in PASMC pH homeostasis are mediated by the transcriptional regulator hypoxia-inducible factor 1 (HIF-1). "
|2.||NF-kappa B (NF-kB)
|5.||130-nm albumin-bound paclitaxel
|6.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|7.||Messenger RNA (mRNA)
|8.||Transcription Factors (Transcription Factor)
|9.||Carbonic Anhydrases (Carbonic Anhydrase)
|1.||Drug Therapy (Chemotherapy)
|5.||Heterologous Transplantation (Xenotransplantation)