|1.||Kawamoto, Takeshi: 5 articles (01/2015 - 02/2008)|
|2.||Kato, Yukio: 5 articles (01/2015 - 02/2008)|
|3.||Kijima, Hiroshi: 5 articles (01/2015 - 02/2008)|
|4.||Fujimoto, Katsumi: 5 articles (01/2015 - 02/2008)|
|5.||Morohashi, Satoko: 4 articles (01/2015 - 04/2010)|
|6.||Wu, Yunyan: 4 articles (01/2015 - 04/2010)|
|7.||Desprez, Pierre-Yves: 4 articles (01/2013 - 11/2007)|
|8.||Sato, Fuyuki: 4 articles (04/2012 - 02/2008)|
|9.||Noshiro, Mitsuhide: 4 articles (04/2012 - 02/2008)|
|10.||McAllister, Sean D: 3 articles (01/2013 - 11/2007)|
01/26/2015 - "In this issue of Developmental Cell, Wang and Baker (2015) demonstrate unsuspected cross-talk between bHLH transcription factors, important regulators of organogenesis, with the Hippo tumor suppressor pathway to ensure that inappropriately differentiating cells are eliminated during development. "
05/01/2014 - "This study establishes a unique model in which determinants of CNS tumor diversity can be parsed out and reveals that both mutation and expression of neurogenic bHLH transcription factors contribute to CNS tumor diversity. "
01/01/2015 - "DEC1 [basic helix-loop-helix (BHLH) E40/Stra13/Sharp2] and DEC2 (BHLHE41/Sharp1) are BHLH transcription factors that are associated with the regulation of apoptosis, cell proliferation, and circadian rhythms, as well as malignancy in various cancers. "
05/01/2014 - "Furthermore, proneural basic helix-loop-helix (bHLH) transcription factors, Ngn2 (NEUROG2) or NeuroD1, were expressed along with HRasV12 and AKT in neocortical radial glia, leading to the formation of highly lethal ATRT like tumors. "
01/01/2014 - "Numerous basic-helix-loop-helix (bHLH) transcription factors (TF) have been found to play important roles in tumor growth and progression. "
|2.||Breast Neoplasms (Breast Cancer)
06/18/2009 - "In this study, using a yeast two-hybrid screening technique, we identified a novel ERbeta1-interacting protein, inhibitor of differentiation-1 (Id1), which is a dominant negative regulator of bHLH transcription factors, and promotes cell proliferation in breast cancer cells. "
01/01/2013 - "The basic helix-loop-helix (bHLH) proteins in breast cancer progression."
09/01/2006 - "Recent data indicate that in a myoblastic cell line and in a breast cancer cell line, BMP-2 increases the expression of Id-1, a negative regulator of basic helix-loop-helix transcription factors, but the role of BMP-2 stimulated Id-1 expression in the kidney has not been further characterized. "
04/01/2011 - "Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells."
|3.||Spinal Cord Injuries (Spinal Cord Injury)
04/01/2012 - "DEC1 (BHLHE40/Stra13/Sharp2) and DEC2 (BHLHE41/Sharp1) are basic helix-loop-helix (bHLH) transcription factors that are involved in the regulation of apoptosis, cell proliferation, circadian rhythms and the response to hypoxia. "
04/01/2010 - "DEC1 (BHLHB2/Stra13/Sharp2) and DEC2 (BHLHB3/Sharp1) are basic helix-loop-helix (bHLH) transcription factors that are involved in circadian rhythms, differentiation and the responses to hypoxia. "
02/01/2008 - "DEC1 (BHLHB2/Sharp2/Stra13) and DEC2 (BHLHB3/Sharp1) are basic-helix-loop-helix (bHLH) transcription factors, involved in cellular differentiation, responses to hypoxia and circadian rhythms. "
02/01/2004 - "These experiments suggest that XREs, E-boxes, and PAS domain/basic helix-loop-helix transcription factors (bHLH-PAS) contribute to preferential rabbit Aldh1a1 promoter activity in the cornea, implicating hypoxia-related pathways."
01/01/2009 - "Hypoxia-Inducible Factors (HIFs) are heterodimeric oxygen-sensitive basic helix-loop-helix transcription factors that play central roles in cellular adaptation to low oxygen environments. "
|5.||Retinoblastoma (Glioblastoma, Retinal)
08/01/2005 - "Alternatively, members of the Id family, for example, Id 2 can also bind to non-bHLH proteins such as retinoblastoma (Rb) and ETS-TCF to modulate their activities. "
03/28/2006 - "Id2 is a natural inhibitor of the basic helix-loop-helix transcription factors and the retinoblastoma tumor suppressor protein. "
10/15/2004 - "Id2, a negative regulator of basic helix-loop-helix transcription factors, has also been proposed as a Myc target gene that drives the proliferative response of Myc by binding to and overriding the checkpoint functions of the retinoblastoma tumor suppressor protein. "
10/05/2000 - "Id2 is a dominant-negative antagonist of basic helix-loop-helix transcription factors and proteins of the retinoblastoma (Rb) family. "
02/20/2004 - "These activities have been related to the recognized ability of Id proteins to antagonize basic helix loop helix transcription factors and proteins of the Retinoblastoma tumor suppressor family. "
|1.||DNA (Deoxyribonucleic Acid)
|2.||Proteins (Proteins, Gene)
|4.||Complementary DNA (cDNA)
|5.||Inhibitor of Differentiation Proteins
|6.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|7.||Intercellular Signaling Peptides and Proteins (Growth Factors)
|8.||Nuclear Localization Signals (Nuclear Localization Signal)
|9.||Bone Morphogenetic Proteins (Bone Morphogenetic Protein)