|1.||Jo, Dong-Gyu: 5 articles (07/2013 - 04/2003)|
|2.||Jung, Yong-Keun: 5 articles (07/2013 - 04/2003)|
|3.||Wasco, Wilma: 4 articles (12/2011 - 04/2005)|
|4.||Buxbaum, Joseph D: 4 articles (12/2011 - 10/2004)|
|5.||Chang, Jae-Woong: 3 articles (07/2013 - 05/2003)|
|6.||Kim, Yong-Sun: 3 articles (12/2011 - 04/2005)|
|7.||Choi, Jin-Kyu: 3 articles (12/2011 - 04/2005)|
|8.||Choi, Eun-Kyoung: 3 articles (12/2011 - 04/2005)|
|9.||Lee, Joo-Yong: 2 articles (07/2013 - 02/2004)|
|10.||Jang, Changhwan: 2 articles (12/2011 - 02/2011)|
|1.||Alzheimer Disease (Alzheimer's Disease)
02/01/2004 - "In this study, we hypothesized that calsenilin might be involved in the neurodegeneration of Alzheimer's disease and examined calsenilin expression in Alzheimer's disease. "
04/04/2005 - "Our findings suggest that calsenilin overexpression in both neurons and reactive astrocytes may play an important role in apoptosis and in Alzheimer's disease pathology."
04/04/2005 - "In Alzheimer's disease brains, the caspase-derived fragment of calsenilin was only detected in cytosolic fraction. "
04/04/2005 - "Although calsenilin is primarily expressed in neurons, its immunoreactivity was also detected in reactive astrocytes of the Alzheimer's disease brains. "
04/04/2005 - "Here, we investigated the histochemical localization of calsenilin and its expression levels in the brains of sporadic Alzheimer's disease. "
09/01/2007 - "Distribution of downstream regulatory element antagonist modulator (DREAM) in rat spinal cord and upregulation of its expression during inflammatory pain."
12/01/2012 - "Nitric oxide modulated the expression of DREAM/calsenilin/KChIP3 in inflammatory pain of rats."
03/01/2011 - "Downstream Regulatory Element Antagonist Modulator (DREAM) protein modulates pain by regulating prodynorphin gene transcription. "
01/01/2010 - "The transcriptional repressor DREAM (downstream regulatory element antagonist modulator) controls the expression of prodynorphin and has been involved in the modulation of endogenous responses to pain. "
09/01/2007 - "A previous knockout study revealed the critical role of downstream regulatory element antagonist modulator (DREAM) in pain processing in the spinal cord by transcriptional regulation of prodynorphin (PPD) gene. "
07/01/2013 - "The expression of calsenilin was found to be increased in brain following experimental ischemic stroke. "
07/01/2013 - "Calsenilin contributes to neuronal cell death in ischemic stroke."
07/01/2013 - "The aim of the present study was to characterize the role of calsenilin as a regulator of the γ-secretase cleavage of Notch in ischemic stroke. "
07/01/2013 - "These findings establish a specific molecular mechanism by which the induction of calsenilin enhances Notch activation in ischemic stroke, and identify calsenilin as an upstream of the γ-secretase cleavage of Notch."
12/01/2011 - "The purpose of this study was to determine whether calsenilin, a presenilin-interacting protein, has a functional role in PS1/γ-secretase-mediated N-cadherin ε-cleavage using Western blot analysis, RT-PCR, immunoprecipitation, subcellular fractionation, biotinylation, and a luciferase reporter assay in SH-SY5Y neuroblastoma cells. "
04/03/2003 - "In addition, immunoreactivity of calsenilin in the hippocampus derived from human epilepsy patient was significantly decreased compared with normal brain. "
02/11/2011 - "In addition, increased levels of calsenilin are observed in the brains of Alzheimer's disease and epilepsy patients. "
12/19/2006 - "[Changes of potassium channels Kv4.2, Kv4.3 and Kv channel interacting protein 1 in amygdala kindling epilepsy: experiment with rats]."
04/03/2003 - "Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients."
|1.||Amyloid Precursor Protein Secretases (beta-Secretase)
|7.||Mitogen-Activated Protein Kinase 3
|8.||Messenger RNA (mRNA)