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Classical Pathway Complement C3 Convertase

A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of COMPLEMENT 4B and COMPLEMENT 2A (C4b2a).
Also Known As:
Complement C3 Convertase, Classical Pathway; C3 Convertase (C4b2a); Classical C3 Convertase; Classical Pathway C3 Convertase; C3 Convertase, Classical
Networked: 9 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Tomlinson, S: 1 article (03/2015)
2. Elvington, M: 1 article (03/2015)
3. Schepp-Berglind, J: 1 article (03/2015)
4. Atkinson, John P: 1 article (12/2012)
5. Hintermeyer, Mary K: 1 article (12/2012)
6. Chase, Nicole M: 1 article (12/2012)
7. Densen, Peter: 1 article (12/2012)
8. Casper, James T: 1 article (12/2012)
9. Miller, Elizabeth C: 1 article (12/2012)
10. Ruiz-Gómez, Gloria: 1 article (09/2009)

Related Diseases

1. Infection
2. Colitis
3. Systemic Lupus Erythematosus (Libman-Sacks Disease)
4. Hemolysis
5. Amyloid Plaque

Related Drugs and Biologics

1. Mannose-Binding Lectin (Mannan-Binding Lectin)
2. Sodium
3. Opsonin Proteins (Opsonins)
4. Dextrans (Dextran)
5. Complement System Proteins (Complement)
6. complement 4 nephritic factor
7. Immunoglobulin G (IgG)
8. Edetic Acid (EDTA)
9. Carrier Proteins (Binding Protein)
10. Autoantibodies