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Protein Kinase C-alpha

A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.
Also Known As:
Protein Kinase C alpha; Protein Kinase C(alpha); PKC alpha Serine Threonine Kinase; Serine-Threonine Kinase, PKC-alpha; PKC-alpha Serine-Threonine Kinase
Networked: 234 relevant articles (4 outcomes, 26 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Liu, Jer-Yuh: 8 articles (01/2015 - 09/2005)
2. Huang, Chih-Yang: 6 articles (01/2015 - 09/2005)
3. Lahn, Michael: 6 articles (03/2006 - 04/2003)
4. Hsieh, Yi-Hsien: 4 articles (01/2015 - 02/2007)
5. Leitges, Michael: 4 articles (07/2009 - 08/2004)
6. Hsieh, Yih-Shou: 4 articles (02/2008 - 09/2005)
7. Holmlund, Jon T: 4 articles (10/2005 - 04/2002)
8. Hwang, Jin-Ming: 3 articles (04/2012 - 04/2010)
9. Bradford, Andrew P: 3 articles (12/2009 - 12/2006)
10. Haughian, James M: 3 articles (12/2009 - 12/2006)

Related Diseases

1. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
2. Lung Neoplasms (Lung Cancer)
3. Brain Ischemia (Cerebral Ischemia)
4. Hypertriglyceridemia
5. Hyperinsulinism (Hyperinsulinemia)

Related Drugs and Biologics

1. aprinocarsen
2. Cisplatin (Platino)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. gemcitabine
5. Glycerol (Glycerine)
6. Fructose
7. ISIS 3521
8. Messenger RNA (mRNA)
9. Phosphotransferases (Kinase)
10. Zinc

Related Therapies and Procedures

1. Hyperbaric Oxygenation
2. Drug Therapy (Chemotherapy)
3. Injections
4. Transplants (Transplant)
5. Intravenous Infusions