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I-kappa B Kinase

A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.
Also Known As:
CHUK Kinase; Conserved Helix-Loop-Helix Ubiquitous Kinase; I Kappa B alpha-Associated Protein Kinase; I kappa B Kinase; IKBKB; IKK 1 Kinase; IKK 2 Kinase; IKK alpha; IKK beta; IKK epsilon; IKK gamma; IKKepsilon; IkappaB Kinase; IkappaB Kinase alpha; IkappaB Kinase beta; IkappaB Kinase epsilon; IkappaB Kinase gamma; IkappaBalpha Kinase; NF-kappaB Essential Modifier; NK-kappa B-Activating Kinase NAK; B Kinase, I-kappa; Conserved Helix Loop Helix Ubiquitous Kinase; Essential Modifier, NF-kappaB; I Kappa B alpha Associated Protein Kinase; Kinase alpha, IkappaB; Kinase beta, IkappaB; Kinase epsilon, IkappaB; Kinase, I-kappa B; Kinase, IkappaB; NF kappaB Essential Modifier; NK kappa B Activating Kinase NAK
Networked: 417 relevant articles (17 outcomes, 33 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Karin, Michael: 22 articles (03/2013 - 05/2003)
2. Aggarwal, Bharat B: 11 articles (11/2010 - 02/2003)
3. Pasparakis, Manolis: 8 articles (10/2008 - 10/2003)
4. Maeda, Shin: 7 articles (04/2009 - 02/2005)
5. Itai, Akiko: 7 articles (01/2009 - 10/2004)
6. Muto, Susumu: 7 articles (01/2009 - 10/2004)
7. Baldwin, Albert S: 7 articles (10/2008 - 06/2003)
8. Yamaoka, Shoji: 6 articles (03/2008 - 10/2003)
9. Yull, Fiona E: 5 articles (07/2010 - 01/2003)
10. Shibata, Wataru: 5 articles (03/2010 - 09/2007)

Related Diseases

1. Inflammation
2. Colitis
3. Neoplasms (Cancer)
4. Insulin Resistance
5. Pneumonia (Pneumonitis)

Related Drugs and Biologics

1. NF-kappa B (NF-kB)
2. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3. Cytokines
4. Phosphotransferases (Kinase)
5. NF-kappaB inhibitor alpha
6. Interleukin-6 (Interleukin 6)
7. N- (3,5- bis(trifluoromethyl)phenyl)- 5- chloro- 2- hydroxybenzamide
8. 4(2'- aminoethyl)amino- 1,8- dimethylimidazo(1,2- a)quinoxaline
9. L-Selectin
10. Dextran Sulfate

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Artificial Respiration (Mechanical Ventilation)
3. Transplants (Transplant)
4. Electroacupuncture
5. Resuscitation