|1.||Igarashi, Peter: 8 articles (01/2010 - 10/2002)|
|2.||Hattersley, A T: 8 articles (12/2006 - 01/2000)|
|3.||Hattersley, Andrew T: 7 articles (07/2009 - 01/2002)|
|4.||Hiesberger, Thomas: 7 articles (01/2009 - 10/2002)|
|5.||Ellard, Sian: 7 articles (07/2008 - 12/2002)|
|6.||Bellanné-Chantelot, Christine: 6 articles (10/2010 - 04/2004)|
|7.||Bingham, Coralie: 6 articles (07/2008 - 04/2002)|
|8.||Ellard, S: 6 articles (12/2006 - 01/2001)|
|9.||Pontoglio, Marco: 5 articles (01/2010 - 10/2002)|
|10.||Bingham, C: 5 articles (12/2006 - 01/2001)|
09/01/2008 - "The aim of this study was to systematically analyze clear cell carcinoma of the pancreas and its unique biomarker hepatocyte nuclear factor-1beta. "
04/01/2007 - "Recent microarray studies have shown that the expression of hepatocyte nuclear factor-1beta (HNF-1beta) was significantly up-regulated in clear cell carcinoma (CCC) of the ovary. "
01/01/2015 - "We evaluated the diagnostic value of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma. "
01/01/2015 - "Diagnostic value of dual detection of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma."
12/01/2012 - "Hepatocyte nuclear factor 1-beta (HNF1β) has recently emerged as a relatively sensitive and specific marker for ovarian clear cell carcinoma. "
|2.||Type 2 Diabetes Mellitus (MODY)
10/01/1999 - "These studies strongly suggest that heterozygous mutations in the HNF-1beta gene are associated with a syndrome characterized by MODY and severe, non-diabetic renal disease. "
01/01/2008 - "Mutation in hepatocyte nuclear factor-1beta gene (TCF2) associated with MODY. "
12/01/2004 - "These results suggest that HNF-1beta gene mutations may be associated with nondiabetic renal dysfunction and diabetes in Chinese, but they are responsible for only a small percentage of early onset or multiple affected diabetes pedigrees including MODY."
12/01/2004 - "Mutation of HNF-1beta gene has been reported in early onset diabetes or MODY families and this gene has been defined as MODY5 gene. "
01/01/2002 - "Identification of a gain-of-function mutation in the HNF-1beta gene in a Japanese family with MODY."
|3.||Clear Cell Adenocarcinoma
07/01/2007 - "Recent studies have noted specific expression of hepatocyte nuclear factor (HNF) 1beta in ovarian clear-cell adenocarcinoma (CCA). "
07/01/2007 - "Immunohistochemical detection of hepatocyte nuclear factor 1beta in ovarian and endometrial clear-cell adenocarcinomas and nonneoplastic endometrium."
03/01/2007 - "Specific expression of hepatocyte nuclear factor-1beta in the ovarian clear cell adenocarcinoma and its application to cytological diagnosis."
03/01/2007 - "Previous studies using DNA microarrays have demonstrated that hepatocyte nuclear factor-1beta (HNF-1beta) is expressed specifically in clear cell adenocarcinoma (CCC). "
01/01/2015 - "A review on hepatocyte nuclear factor-1beta and tumor."
01/01/2006 - "Our results indicate that HNF-1beta is an excellent molecular marker for ovarian clear cell tumors, including benign, borderline and malignant lesions. "
01/01/2006 - "In nine of the 12 cases, distinct nuclear immunostaining for HNF-1beta was detected in the endometriotic epithelium, as well as in the clear cell tumor. "
01/01/2006 - "All of the 30 clear cell tumors, including borderline and benign ones, showed immunohistochemical expression of HNF-1beta in the nucleus, while other types of ovarian epithelial tumors (endometrioid, serous, mucinous, and Brenner tumors) rarely expressed it. "
02/01/2005 - "HNF-1beta was not expressed or expressed very weakly in other papillary, follicular, and Hurthle cancer cell lines and primary cultures of normal thyroid cells and benign thyroid conditions. "
04/01/2009 - "Recent studies based on genome-wide expression analysis technology have noted specific expression of hepatocyte nuclear factor-1beta (HNF-1beta) in endometriosis and CCC, suggesting that early differentiation into the clear cell lineage takes place in the endometriosis. "
01/01/2006 - "HNF-1beta expression was observed either in atypical endometriosis (four cases), or in endometriosis of a reactive nature (five cases). "
11/01/2009 - "HNF-1beta is also expressed in ovarian endometriosis, which is a probable origin of clear cell carcinoma. "
06/01/2006 - "Clear-cell carcinomas are characterized by mutations of TGFbetaR2 and over-expression of HNF-1beta, and probably arise from ovarian endometriosis. "
01/01/2006 - "Expression of hepatocyte nuclear factor-1beta (HNF-1beta) in clear cell tumors and endometriosis of the ovary."
|1.||Hepatocyte Nuclear Factor 1-beta
|2.||Transcription Factors (Transcription Factor)
|3.||DNA (Deoxyribonucleic Acid)
|4.||Coenzyme A (CoA)
|5.||papillary Thyroid cancer
|6.||Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)
|9.||Renal cysts and diabetes syndrome
|10.||insulin promoter factor 1