|1.||Matsuda, Yoko: 7 articles (09/2014 - 02/2010)|
|2.||Ishiwata, Toshiyuki: 7 articles (09/2014 - 02/2010)|
|3.||Bellusci, Saverio: 6 articles (05/2015 - 02/2005)|
|4.||Naito, Zenya: 6 articles (09/2014 - 02/2010)|
|5.||Ezzat, Shereen: 6 articles (11/2012 - 06/2007)|
|6.||Wilkie, Andrew O M: 5 articles (01/2014 - 02/2002)|
|7.||Jabs, Ethylin Wang: 5 articles (05/2013 - 05/2005)|
|8.||Asa, Sylvia L: 5 articles (11/2012 - 06/2007)|
|9.||Chen, Lin: 4 articles (05/2013 - 08/2003)|
|10.||Warburton, David: 4 articles (10/2009 - 02/2005)|
|1.||Stomach Neoplasms (Stomach Cancer)
06/01/2015 - "Fibroblast growth factor receptor 2 (FGFR2) amplification has been reported to be a target for treatment in gastric cancer. "
02/10/2015 - "Fibroblast growth factor receptor 2 (FGFR2)-targeted therapy has attracted considerable attention as novel anticancer agents in gastric cancer (GC). "
01/01/2015 - "Evaluation of Fibroblast Growth Factor Receptor 2 Expression, Heterogeneity and Clinical Significance in Gastric Cancer."
11/01/2013 - "Fibroblast growth factor receptor 2: a therapeutic target in gastric cancer."
02/01/2012 - "Meanwhile, an integrated analysis of 11 gastric cancer cell lines revealed that four cell lines amplified fibroblast growth factor receptor 2, with truncated forms observed in two of the cell lines. "
|2.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "The highly significant association of the Fibroblast growth factor receptor 2 (FGFR2) locus with breast cancer risk has been replicated in multiple genome association study; however, it's mechanism of action remains unclear. "
01/01/2014 - "A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North India."
03/01/2013 - "Genomewide association studies have consistently found variants in fibroblast growth factor receptor 2 (FGFR2) to be associated with breast cancer. "
06/15/2012 - "Our study examines FGFR2 protein expression in breast cancer and determines its associations with clinicopathological features and survival. "
08/01/2010 - "In the entire study population, 9/10 SNPs in fibroblast growth factor receptor 2 (FGFR2) were significantly associated with breast cancer after adjusting for age, race and European ancestry [odds ratios (OR) range 1.17-1.81]. "
|3.||Acrocephalosyndactylia (Apert Syndrome)
08/01/2010 - "The changes in form characterized in this study will help to elucidate the mechanisms through which the Pro253Arg mutation in fibroblast growth factor receptor 2 affects craniofacial development and causes Apert syndrome."
09/01/2007 - "The frequency of the most common sporadic Apert syndrome mutation (C755G) in the human fibroblast growth factor receptor 2 gene (FGFR2) is 100-1,000 times higher than expected from average nucleotide substitution rates based on evolutionary studies and the incidence of human genetic diseases. "
01/01/2015 - "Molecular analysis of exons 8, 9 and 10 of the fibroblast growth factor receptor 2 (FGFR2) gene in two families with index cases of Apert Syndrome."
01/01/2014 - "Apert syndrome is an autosomal dominantly inherited disorder caused by missense mutations in fibroblast growth factor receptor 2 (FGFR2). "
01/01/2014 - "A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation."
07/01/2009 - "Aberrant FGF signalling is implicated in tumourigenesis, with several cancer studies reporting FGF-10 or FGFR2B upregulation or identifying activating mutations in Fgfr2. "
12/01/2015 - "Cells were examined for expression of C-X-C chemokine receptor 4 (CXCR4), fibroblast growth factor receptor 2 (FGFR2) and stromal-derived factor 1 (SDF1) by RT-PCR, western blot, ELISA and immunohistochemical staining of xenografted tumors. "
02/01/2015 - "Fibroblast growth factor receptor 2: a new potential therapeutic target for human cancer."
01/01/2015 - "Intratumoral heterogeneity and discordant FGFR2b expression in primary tumors and metastatic lymph nodes are common in GC."
10/01/2012 - "We believe that the determination of fibroblast growth factor receptor 2 amplification status could allow the identification of a subset of cancers sensitive to targeted fibroblast growth factor receptor 2 inhibitor-based therapy."
10/01/2012 - "In this study, fibroblast growth factor receptor 2 amplification status was evaluated by fluorescence in situ hybridization in 313 surgically resected gastric carcinoma tissues, and the results were validated by quantitative real-time polymerase chain reaction. "
05/01/2015 - "Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach."
10/01/2012 - "Gastric carcinoma with fibroblast growth factor receptor 2 amplification was found to be associated with advanced disease and a poor prognosis. "
10/01/2012 - "Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma."
12/09/2004 - "Here, we investigated the molecular mechanisms underlying the inhibition of human urothelial carcinoma cell growth following FGFR2b expression. "
|2.||tyrosine receptor (receptor, tyrosine)
|3.||Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)
|5.||Messenger RNA (mRNA)
|6.||DNA (Deoxyribonucleic Acid)
|9.||Transforming Growth Factor beta (TGF-beta)
|10.||Vitamin A (Retinol)
|3.||Heterologous Transplantation (Xenotransplantation)
|4.||Drug Therapy (Chemotherapy)