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Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)

A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
Also Known As:
Fibroblast Growth Factor Receptor 2; Receptor, Fibroblast Growth Factor, Type 2; BEK Fibroblast Growth Factor Receptor; BEK Fibroblast Growth Factor Receptor Kinase; BEK Protein Tyrosine Kinase; Bek Fgf Receptor Kinase; Bek-Related Fibroblast Growth Factor-Receptor-1; CD332 Antigen; FGFR2 Protein; FGFR2b; FGFR2c; Fibroblast Growth Factor Receptor 2b; Fibroblast Growth Factor Receptor 2c; Fibroblast Growth Factor Receptors 2; Fibroblast Growth Factor Receptors 2b; Receptor, Fibroblast Growth Factor 2b; Receptor, Fibroblast Growth Factor 2c; Antigen, CD332; Bek Related Fibroblast Growth Factor Receptor 1
Networked: 496 relevant articles (10 outcomes, 46 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Bellusci, Saverio: 13 articles (01/2020 - 06/2004)
2. Jabs, Ethylin Wang: 9 articles (01/2022 - 05/2005)
3. Borad, Mitesh J: 7 articles (01/2022 - 08/2014)
4. Richtsmeier, Joan T: 7 articles (01/2022 - 11/2010)
5. Wilkie, Andrew O M: 7 articles (01/2022 - 02/2002)
6. Belleudi, Francesca: 7 articles (10/2021 - 02/2016)
7. Ranieri, Danilo: 7 articles (10/2021 - 02/2016)
8. Torrisi, Maria Rosaria: 7 articles (10/2021 - 02/2016)
9. Pollock, Pamela M: 7 articles (04/2021 - 07/2008)
10. Ezzat, Shereen: 7 articles (01/2018 - 06/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Stomach Neoplasms (Stomach Cancer)
3. Acrocephalosyndactylia (Apert Syndrome)
4. Carcinoma (Carcinomatosis)
5. Craniosynostoses (Craniosynostosis)

Related Drugs and Biologics

1. bemarituzumab
2. Claudins
3. erdafitinib
4. Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)
5. Cisplatin (Platino)
6. AZD4547
7. Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)
8. Proteins (Proteins, Gene)
9. Protein Isoforms (Isoforms)
10. Messenger RNA (mRNA)

Related Therapies and Procedures

1. Therapeutics
2. Sutures (Suture)
3. Drug Therapy (Chemotherapy)
4. Distraction Osteogenesis
5. Chemoradiotherapy