|1.||Salgia, Ravi: 9 articles (12/2015 - 02/2002)|
|2.||Hamamura, Kazunori: 5 articles (12/2012 - 08/2005)|
|3.||Furukawa, Keiko: 5 articles (12/2012 - 08/2005)|
|4.||Furukawa, Koichi: 5 articles (12/2012 - 08/2005)|
|5.||Natarajan, Viswanathan: 4 articles (12/2015 - 01/2008)|
|6.||Hu, Chi-Tan: 4 articles (10/2015 - 12/2011)|
|7.||Wu, Jia-Ru: 4 articles (10/2015 - 12/2011)|
|8.||Wu, Wen-Sheng: 4 articles (10/2015 - 12/2011)|
|9.||Pan, Siou-Mei: 4 articles (10/2015 - 12/2011)|
|10.||Cheng, Chuan-Chu: 4 articles (10/2015 - 12/2011)|
10/01/2008 - "Our previous study indicates that Brk promotes cell migration and tumor invasion by phosphorylating the focal adhesion protein paxillin. "
03/01/2003 - "In this study we evaluated the levels of paxillin and p130CAS in feline and canine mammary tumor tissues at different stages of malignancy. "
12/01/2015 - "Furthermore, HPW-RX40 inhibited detachment-induced activation of FAK and the downstream phosphorylation of Src and paxillin, but did not affect this pathway in adherent cancer cells. "
07/01/2015 - "PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2."
01/01/2015 - "Bioinformatics analysis indicated that the mechanism underlying the tumor suppressor role of miR-132 in CRC cells may play a role in tumor suppression by targeting paxillin. "
|2.||Breast Neoplasms (Breast Cancer)
08/27/2009 - "In conclusion, our studies show that PAR2 agonists facilitate breast cancer cell chemokinesis through the G(alphai)-c-Src-JNK-paxillin signaling pathway."
03/01/2007 - "In the current study, we sought to explore the relationship further between paxillin expression and clinicopathologic features and clinical outcome in breast cancer. "
06/15/1999 - "This study is the first demonstration of regulation of paxillin expression by a polypeptide growth factor, and it suggests a potential role for paxillin in the HER2 pathway in breast cancer."
11/15/2014 - "MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells."
01/01/2014 - "In addition to its structural functions, paxillin has more recently been shown to function as a regulator of cell division-mediating steroid-triggered meiosis in oocytes as well as steroid- and growth factor-induced proliferation in prostate and breast cancer. "
01/01/2011 - "The purpose of the study was to investigate the expression of TOP2A, EZH2 and paxillin in relation to classic prognostic parameters and their significance as prognostic markers in imprints of resected breast carcinomas. "
01/01/2015 - "Paxillin (PXN) gene has been reported to act as an oncogene in many malignancies and play important roles in the development of human carcinomas. "
01/01/2015 - "Fascin-1 and paxillin were expressed in 58% and 43% of infiltrating duct carcinoma (IDC) cases. "
01/01/2015 - "We investigated fascin-1 and paxillin expression in breast carcinoma, and we have related these results to the established prognostic factors. "
03/01/2007 - "Paxillin expression was identified in 27.7% of breast carcinomas as diffuse cytoplasmic staining and the expression correlated with HER2 overexpression (p < 0.001). "
|4.||Neoplasm Metastasis (Metastasis)
06/01/2014 - "Both paxillin expression and CAIX expression were associated significantly with larger tumours, a higher tumour-node-metastasis (TNM) stage, lymph node metastasis and invasiveness of SC/ASC and AC. "
01/01/2014 - "Paxillin may be a potential metastasis predictor, and an independent prognosis factor of recurrence. "
01/01/2014 - "Multivariate analyses revealed that recurrence was associated with the rate of regional lymph node metastasis (P = 0.001) and paxillin expression (P = 0.024). "
08/01/2010 - "High expression of paxillin was correlated with a more advanced stage and metastasis in SACC, suggesting that paxillin is a disease marker in advanced SACC and SACC with distant metastasis, and, consequently, may have value as a therapeutic target for SACC."
08/01/2010 - "Paxillin expression was identified in 57.45% of SACC as cytoplasmic staining and the expression was correlated with distant metastasis and clinical stage (P < 0.05), but not with histological type. "
|5.||Colorectal Neoplasms (Colorectal Cancer)
01/01/2015 - "The aim of this study was to investigate the expression of Paxillin in colorectal carcinoma and its significance in clinical prognosis. "
11/01/2011 - "The aim of this study was to investigate the effects of paxillin on proliferation, migration, invasion, adhesion and apoptosis of HCT-8 human colorectal cancer cells in vitro. "
01/01/2015 - "Paxillin was expressed at significantly higher levels in colorectal cancer tissues and might serve as a potential prognostic indicator in patients with colorectal cancer."
01/01/2015 - "Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients."
01/01/2015 - "Higher expression of paxillin and lower expression of miR-145 was observed in colorectal cancer tissues than corresponding paracancerous tissue. "
|2.||Focal Adhesion Protein-Tyrosine Kinases
|5.||Proteins (Proteins, Gene)
|7.||Messenger RNA (mRNA)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)
|5.||Artificial Respiration (Mechanical Ventilation)