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Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)

A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.
Also Known As:
Hemophagocytic Syndrome; Lymphohistiocytosis, Hemophagocytic; Erythrophagocytic Lymphohistiocytosis, Familial; Familial Erythrophagocytic Lymphohistiocytosis; Familial Hemophagocytic Histiocytosis; Familial Hemophagocytic Lymphohistiocytosis; Familial Hemophagocytic Reticulosis; Familial Histiocytic Reticulosis; Hemophagocytic Lymphohistiocytosis Familial -1; Hemophagocytic Lymphohistiocytosis, Familial, 1; Hemophagocytic Reticulosis, Familial; Primary Hemophagocytic Hymphohistiocytosis; Primary Hemophagocytic Lymphohistiocytosis; Reticulosis, Familial Histiocytic; Erythrophagocytic Lymphohistiocytoses, Familial; Familial Erythrophagocytic Lymphohistiocytoses; Familial Hemophagocytic Histiocytoses; Familial Hemophagocytic Lymphocytoses; Familial Hemophagocytic Lymphohistiocytoses; Familial Hemophagocytic Reticuloses; Familial Histiocytic Reticuloses; Hemophagocytic Histiocytoses, Familial; Hemophagocytic Histiocytosis, Familial; Hemophagocytic Hymphohistiocytoses, Primary; Hemophagocytic Hymphohistiocytosis, Primary; Hemophagocytic Lymphocytoses, Familial; Hemophagocytic Lymphocytosis, Familial; Hemophagocytic Lymphohistiocytoses; Hemophagocytic Lymphohistiocytoses, Familial; Hemophagocytic Lymphohistiocytoses, Primary; Hemophagocytic Lymphohistiocytosis Familial 1; Hemophagocytic Lymphohistiocytosis, Primary; Hemophagocytic Reticuloses, Familial; Hemophagocytic Syndrome, Infection Associated; Histiocytic Reticuloses, Familial; Histiocytic Reticulosis, Familial; Histiocytoses, Familial Hemophagocytic; Histiocytosis, Familial Hemophagocytic; Hymphohistiocytoses, Primary Hemophagocytic; Hymphohistiocytosis, Primary Hemophagocytic; Infection-Associated Hemophagocytic Syndrome; Lymphocytoses, Familial Hemophagocytic; Lymphocytosis, Familial Hemophagocytic; Lymphohistiocytoses, Familial Erythrophagocytic; Lymphohistiocytoses, Familial Hemophagocytic; Lymphohistiocytoses, Hemophagocytic; Lymphohistiocytoses, Primary Hemophagocytic; Lymphohistiocytosis, Familial Erythrophagocytic; Lymphohistiocytosis, Familial Hemophagocytic; Lymphohistiocytosis, Primary Hemophagocytic; Primary Hemophagocytic Hymphohistiocytoses; Primary Hemophagocytic Lymphohistiocytoses; Reticuloses, Familial Hemophagocytic; Reticuloses, Familial Histiocytic; Reticulosis, Familial Hemophagocytic; Familial Hemophagocytic Lymphocytosis; Hemophagocytic Lymphohistiocytosis, Familial; Hemophagocytic Syndrome, Infection-Associated; Hemophagocytic Syndrome, Reactive; Hemophagocytic Syndromes; Reactive Hemophagocytic Syndrome
Networked: 1909 relevant articles (109 outcomes, 84 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infections
2. Pancytopenia
3. Visceral Leishmaniasis (Kala Azar)
4. Macrophage Activation Syndrome
5. COVID-19

Experts

1. Wang, Zhao: 35 articles (08/2022 - 12/2008)
2. Jordan, Michael B: 26 articles (01/2022 - 08/2004)
3. Wang, Yini: 24 articles (08/2022 - 11/2009)
4. Wang, Jingshi: 21 articles (12/2021 - 11/2009)
5. Henter, Jan-Inge: 19 articles (01/2022 - 01/2002)
6. Ishii, Eiichi: 19 articles (11/2020 - 06/2002)
7. Wu, Lin: 17 articles (12/2021 - 12/2008)
8. Janka, Gritta: 16 articles (01/2022 - 01/2002)
9. Filipovich, Alexandra H: 16 articles (12/2014 - 01/2002)
10. Ehl, Stephan: 15 articles (01/2022 - 07/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hemophagocytic Lymphohistiocytosis:
1. ruxolitinibIBA
2. Etoposide (VP 16)FDA LinkGeneric
3. Cyclosporine (Ciclosporin)FDA LinkGeneric
4. Dexamethasone (Maxidex)FDA LinkGeneric
5. CytokinesIBA
6. SteroidsIBA
7. Rituximab (Mabthera)FDA Link
8. Adrenal Cortex Hormones (Corticosteroids)IBA
9. MethylprednisoloneFDA LinkGeneric
10. GlucocorticoidsIBA

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Hematopoietic Stem Cell Transplantation
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Aftercare (After-Treatment)