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Cyclin-Dependent Kinase 2

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
Also Known As:
CDK2 Protein; Cdc2-Related Protein Kinase; p33cdk2 Kinase; Cdc2 Related Protein Kinase; Cyclin Dependent Kinase 2; Cdk2 Protein Kinase
Networked: 186 relevant articles (3 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Keyomarsi, Khandan: 4 articles (04/2012 - 03/2004)
2. Kung, Hsiang-Fu: 2 articles (11/2015 - 06/2007)
3. Li, Ling: 2 articles (11/2015 - 01/2015)
4. Li, Yan: 2 articles (01/2012 - 09/2011)
5. Mann, David J: 2 articles (10/2011 - 07/2010)
6. Child, Emma S: 2 articles (10/2011 - 07/2010)
7. Chwirot, Barbara W: 2 articles (07/2010 - 10/2006)
8. Ku┼║bicki, Lukasz: 2 articles (07/2010 - 10/2006)
9. Burnstein, Kerry L: 2 articles (03/2010 - 11/2003)
10. Choi, Yung Hyun: 2 articles (09/2009 - 06/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
3. Aneuploidy (Aneuploid)
4. Breast Neoplasms (Breast Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Thymidine
3. Agar
4. ABT-100
5. kenpaullone
6. Cyclin E
7. Cyclins
8. Cyclin D1
9. Retinoblastoma Protein
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Chinese Traditional Medicine (Traditional Chinese Medicine)
3. Drug Therapy (Chemotherapy)