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Cortactin

A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
Networked: 227 relevant articles (2 outcomes, 32 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jin, Jong-Shiaw: 9 articles (03/2013 - 09/2007)
2. Weed, Scott A: 8 articles (05/2013 - 08/2003)
3. Yu, Cheng-Ping: 6 articles (06/2011 - 01/2009)
4. Schuuring, Ed: 6 articles (03/2008 - 11/2003)
5. Garcia, Joe G N: 5 articles (11/2015 - 08/2007)
6. Lin, Chih-Kung: 5 articles (03/2013 - 01/2009)
7. Tsai, Wen-Chiuan: 5 articles (03/2013 - 09/2007)
8. Nieh, Shin: 5 articles (03/2013 - 01/2009)
9. Koleske, Anthony J: 5 articles (04/2012 - 03/2007)
10. van Rossum, Agnes G S H: 5 articles (05/2006 - 11/2003)

Related Diseases

1. Renal Cell Carcinoma (Grawitz Tumor)
2. Clear Cell Adenocarcinoma
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Small Interfering RNA (siRNA)
2. Tyrosine (L-Tyrosine)
3. Proteins (Proteins, Gene)
4. fascin
5. Actin-Related Protein 2-3 Complex (Arp2 3 Complex)
6. Epidermal Growth Factor Receptor (EGF Receptor)
7. Matrix Metalloproteinase 14 (MT1-MMP)
8. Cyclin D1
9. Epidermal Growth Factor (EGF)
10. Protein-Tyrosine Kinases (Tyrosine Kinase)

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Drug Therapy (Chemotherapy)