|1.||Cao, Hua: 4 articles (11/2013 - 06/2012)|
|2.||Lieber, André: 4 articles (11/2013 - 06/2012)|
|3.||Leube, Rudolf E: 3 articles (08/2015 - 06/2011)|
|4.||Kant, Sebastian: 3 articles (08/2015 - 06/2011)|
|5.||Krusche, Claudia A: 3 articles (08/2015 - 06/2011)|
|6.||Goerdt, Sergij: 3 articles (01/2014 - 09/2007)|
|7.||Peitsch, Wiebke K: 3 articles (01/2014 - 09/2007)|
|8.||Wang, Hongjie: 3 articles (11/2013 - 06/2012)|
|9.||Richter, Maximilian: 3 articles (11/2013 - 06/2012)|
|10.||Fender, Pascal: 3 articles (11/2013 - 06/2012)|
|1.||Prostatic Neoplasms (Prostate Cancer)
01/01/2014 - "Desmoglein 2 is an independent prognostic factor for aggressive prostate cancer."
08/01/2015 - "This study aims to provide a comprehensive view of the role and regulation of cell-cell adhesion in prostate cancer aggressiveness by examining the functional implications of both E-cadherin and Desmoglein 2 (DSG2). "
01/01/2014 - "In this study we characterized desmoglein expression in normal prostate tissues, and further investigated whether Desmoglein 2 (DSG2) expression specifically can serve as a potential clinical prognostic factor for patients diagnosed with primary prostate cancer. "
08/01/2015 - "PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer."
|2.||Melanoma (Melanoma, Malignant)
01/01/2014 - "To study the role of desmoglein 2 in melanoma cells, melanoma lines containing high endogenous amounts of desmoglein 2 were depleted of the protein by RNA interference. "
01/01/2014 - "In summary, we show that desmoglein 2 expression attenuates migration of melanoma cells. "
12/01/2008 - "Indeed, in tissue microarrays, desmoglein 2 has been demonstrated in a sizable subset of nevi and primary melanomas. "
01/01/2014 - "The mechanism of desmoglein 2 impaired cell migration is mediated by downregulation of secretogranin II. Loss of desmoglein 2 increases expression of secretogranin II, followed by an enhanced migratory activity of melanoma cells. "
01/01/2014 - "We have previously shown that a subtype of melanoma cells express the desmosomal cadherin desmoglein 2 as non-junction-bound cell surface protein in addition to classical cadherins. "
|3.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/01/2007 - "Desmoglein 2 (Dsg2), a component of the desmosomal cell-cell adhesion structure, has been linked to invasion and metastasis in squamous cell carcinomas. "
01/01/2014 - "Prognostic significance of desmoglein 2 and desmoglein 3 in esophageal squamous cell carcinoma."
01/18/2013 - "The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells."
10/01/2008 - "Seventy-eight cases of head and neck squamous cell carcinoma were immunohistochemically stained for desmoglein 1, desmoglein 2, desmoglein 3, p53, bcl-2, vimentin, cyclin D1, p16, p21, p27, E-cadherin, and E2F-1 in paraffin-embedded tissue blocks in a microarray. "
|4.||Pemphigus (Pemphigus Vulgaris)
01/01/1999 - "Internalization of constitutive desmogleins with the subsequent induction of desmoglein 2 in pemphigus lesions."
08/01/2003 - "No involvement of IgG autoantibodies against extracellular domains of desmoglein 2 in paraneoplastic pemphigus or inflammatory bowel diseases."
09/01/2011 - "Pemphigus vulgaris (PV) is a potentially fatal autoimmune disease characterized by the presence of in vivo deposition of antibodies against cell surface antigens desmoglein 1 and desmoglein 2 in the epidermis. "
04/20/2015 - "Desmoglein 2 (Dsg2) is an adhesion protein that is upregulated in many cancers and overexpression of Dsg2 in the epidermis renders mice more susceptible to squamous-derived neoplasia. "
11/01/2003 - "As most striking finding, desmoglein 2 was up-regulated qualitatively in half of all neoplasms examined and showed a significant higher proportion of positive cells in high-risk SCC than in low-risk SCC. "
06/15/2012 - "We previously reported on recombinant adenovirus serotype 3-derived protein (JO-1), which triggers transient opening of intercellular junctions in epithelial tumors through binding to desmoglein 2 (DSG2), and enhances the antitumor effects of several therapeutic monoclonal antibodies. "
|4.||Proteins (Proteins, Gene)
|6.||Biological Markers (Surrogate Marker)
|8.||gamma Catenin (Plakoglobin)
|9.||Transcription Factors (Transcription Factor)
|10.||Messenger RNA (mRNA)