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Wiskott-Aldrich Syndrome Protein Family

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Also Known As:
WAS Protein Family, Member 1; WAS Protein Family, Member 2; WAS Protein Family, Member 3; WASF1 Protein; WASF2 Protein; WASF3 Protein; WASP Protein Family; WAVE1 Protein; WAVE2 Protein; WAVE3 Protein; Wiskott-Aldrich Syndrome Protein Family, Member 1; Wiskott-Aldrich Syndrome Protein Family, Member 2; Wiskott-Aldrich Syndrome Protein Family, Member 3; WASP Family Verprolin Homologous Proteins; Wiskott Aldrich Syndrome Protein Family; Wiskott Aldrich Syndrome Protein Family, Member 1; Wiskott Aldrich Syndrome Protein Family, Member 2; Wiskott Aldrich Syndrome Protein Family, Member 3; WAS Protein Family; WASP-Family Verprolin Homologous Proteins; WAVE Proteins
Networked: 37 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jiang, Wen G: 3 articles (11/2010 - 10/2008)
2. Insall, Robert H: 3 articles (08/2009 - 02/2008)
3. Pollitt, Alice Y: 3 articles (08/2009 - 02/2008)
4. Miki, Hiroaki: 3 articles (04/2005 - 01/2003)
5. Takenawa, Tadaomi: 3 articles (04/2005 - 01/2003)
6. Mu, Xiaoling: 2 articles (08/2013 - 10/2012)
7. Zhang, Jing: 2 articles (08/2013 - 10/2012)
8. Tang, Liangdan: 2 articles (08/2013 - 10/2012)
9. Shen, Liyuan: 2 articles (08/2013 - 10/2012)
10. Xiao, Lin: 2 articles (08/2013 - 10/2012)

Related Diseases

1. Wounds and Injuries (Trauma)
2. Cicatrix (Scar)
3. Neoplasms (Cancer)
4. Wiskott-Aldrich Syndrome (Syndrome, Wiskott-Aldrich)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Cyclic AMP Receptors (Cyclic AMP Receptor)
2. Proteins (Proteins, Gene)
3. Actin-Related Protein 2-3 Complex (Arp2 3 Complex)
4. GTP Phosphohydrolases (GTPases)
5. Actin-Related Protein 2
6. Protein Isoforms (Isoforms)
7. p21-Activated Kinases
8. Multiprotein Complexes
9. Reactive Oxygen Species (Oxygen Radicals)
10. RNA-Directed DNA Polymerase (Reverse Transcriptase)