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Wiskott-Aldrich Syndrome Protein Family

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Also Known As:
WAS Protein Family, Member 1; WAS Protein Family, Member 2; WAS Protein Family, Member 3; WASF1 Protein; WASF2 Protein; WASF3 Protein; WASP Protein Family; WAVE1 Protein; WAVE2 Protein; WAVE3 Protein; Wiskott-Aldrich Syndrome Protein Family, Member 1; Wiskott-Aldrich Syndrome Protein Family, Member 2; Wiskott-Aldrich Syndrome Protein Family, Member 3; WASP Family Verprolin Homologous Proteins; Wiskott Aldrich Syndrome Protein Family; Wiskott Aldrich Syndrome Protein Family, Member 1; Wiskott Aldrich Syndrome Protein Family, Member 2; Wiskott Aldrich Syndrome Protein Family, Member 3; WAS Protein Family; WASP-Family Verprolin Homologous Proteins; WAVE Proteins
Networked: 70 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Cowell, John K: 4 articles (01/2022 - 09/2007)
2. Kennedy, Eileen J: 3 articles (04/2022 - 02/2016)
3. Rottner, Klemens: 3 articles (01/2020 - 10/2002)
4. Jiang, Wen G: 3 articles (11/2010 - 10/2008)
5. Insall, Robert H: 3 articles (08/2009 - 02/2008)
6. Pollitt, Alice Y: 3 articles (08/2009 - 02/2008)
7. Miki, Hiroaki: 3 articles (04/2005 - 01/2003)
8. Takenawa, Tadaomi: 3 articles (04/2005 - 01/2003)
9. Bendzunas, George N: 2 articles (04/2022 - 01/2022)
10. Limaye, Ameya J: 2 articles (04/2022 - 01/2022)

Related Diseases

1. Wounds and Injuries (Trauma)
2. Cicatrix (Scar)
3. Ovarian Epithelial Carcinoma
4. Neoplasms (Cancer)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Cyclic AMP Receptors (Cyclic AMP Receptor)
3. Actin-Related Protein 2-3 Complex (Arp2 3 Complex)
4. Actin-Related Protein 2
5. GTP Phosphohydrolases (GTPases)
6. Protein Isoforms (Isoforms)
7. p21-Activated Kinases
8. Fas Ligand Protein (Fas Ligand)
9. Cyclin-Dependent Kinase 4
10. Actin Depolymerizing Factors (Cofilins)

Related Therapies and Procedures

1. Transjugular Intrahepatic Portasystemic Shunt
2. Therapeutics