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NF-E2-Related Factor 2

A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
Also Known As:
Nfe2l2 Protein; Nrf2 Protein; Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein; NF E2 Related Factor 2
Networked: 121 relevant articles (1 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yamamoto, Masayuki: 10 articles (06/2014 - 07/2007)
2. Pan, Hao: 5 articles (01/2014 - 01/2013)
3. Zhu, Lin: 5 articles (01/2014 - 01/2013)
4. Kensler, Thomas W: 5 articles (04/2011 - 11/2007)
5. Wang, Han-Dong: 4 articles (01/2014 - 05/2009)
6. Biswal, Shyam: 3 articles (04/2015 - 09/2008)
7. Wang, Handong: 3 articles (08/2014 - 01/2013)
8. Zhou, Yuan: 3 articles (01/2014 - 01/2013)
9. Zhang, Mingxin: 3 articles (12/2013 - 01/2012)
10. Zhou, Suna: 3 articles (12/2013 - 01/2012)

Related Diseases

1. Acute Kidney Injury (Acute Renal Failure)
2. Neoplasms (Cancer)
3. Anoxia (Hypoxia)
4. Brain Ischemia (Cerebral Ischemia)
5. Chronic Obstructive Pulmonary Disease (COPD)

Related Drugs and Biologics

1. Heme Oxygenase-1
2. Cytochrome P-450 CYP2E1 (CYP2E1)
3. Iron
4. Chlormethiazole (Clomethiazole)
5. Transcription Factors (Transcription Factor)
6. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
7. Thymidine Monophosphate (TMP)
8. Catalase
9. Phosphotransferases (Kinase)
10. Antioxidants

Related Therapies and Procedures

1. Chemoprevention
2. Immunomodulation
3. Heterologous Transplantation (Xenotransplantation)
4. Ligation
5. Lasers (Laser)