|1.||Yamamoto, Masayuki: 10 articles (06/2014 - 07/2007)|
|2.||Pan, Hao: 5 articles (01/2014 - 01/2013)|
|3.||Zhu, Lin: 5 articles (01/2014 - 01/2013)|
|4.||Kensler, Thomas W: 5 articles (04/2011 - 11/2007)|
|5.||Wang, Han-Dong: 4 articles (01/2014 - 05/2009)|
|6.||Biswal, Shyam: 3 articles (04/2015 - 09/2008)|
|7.||Wang, Handong: 3 articles (08/2014 - 01/2013)|
|8.||Zhou, Yuan: 3 articles (01/2014 - 01/2013)|
|9.||Zhang, Mingxin: 3 articles (12/2013 - 01/2012)|
|10.||Zhou, Suna: 3 articles (12/2013 - 01/2012)|
|1.||Acute Kidney Injury (Acute Renal Failure)
08/01/2014 - "Chlormethiazole, a specific CYP2E1 transcription inhibitor, prevented an increase in catalytic iron in the kidneys, decreased oxidative stress, blocked nuclear translocation of the Nrf2 protein, decreased heme oxygenase-1 upregulation, and provided functional and histological protection against acute kidney injury. "
11/01/2014 - "This study demonstrated that the expression of Nrf2 protein was down-regulated in human malignant skin tumors. "
11/15/2014 - "Constitutive NF-E2-related factor 2 (Nrf2) activation has been recently reported to play a pivotal role in enhancing cell survival and resistance to anticancer drugs in many tumors. "
02/07/2014 - "A novel CXCR3-B chemokine receptor-induced growth-inhibitory signal in cancer cells is mediated through the regulation of Bach-1 protein and Nrf2 protein nuclear translocation."
01/01/2014 - "Recently, the role of NF-E2-related factor 2 (Nrf2) in enhancing chemoradiation sensitivity has been reported in several types of cancers. "
07/01/2013 - "However, many cancers have been found to accumulate NRF2 protein, raising questions of precisely how Nrf2 contributes to carcinogenesis. "
06/21/2013 - "In this study, hypoxia suppressed Nrf2 protein, and its hypoxic suppression was not recovered with knockdown of the Nrf2 repressor Keap1. "
09/03/2010 - "Induction of cereblon by NF-E2-related factor 2 in neuroblastoma cells exposed to hypoxia-reoxygenation."
12/15/2011 - "Protein content of XO, superoxide dismutase 1 (Cu,ZnSOD), catalase and myoglobin (Mb), as well as the nuclear content of hypoxia inducible factor 1α (HIF-1α) and NF-E2-related factor 2 (Nrf2), were measured in muscle biopsies collected before and after the breath-hold trials. "
|4.||Brain Ischemia (Cerebral Ischemia)
07/31/2015 - "Another finding in this study was that the anti-neutrophil effect of TMP was accompanied by a further elevated expression of NF-E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) in neutrophils after cerebral ischemia. "
09/01/2013 - "Another finding in this study was that the anti-inflammatory and neuroprotective effects of TMP were accompanied by a further elevated expression of NF-E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) in ipsilateral neurons and macrophages/microglia after cerebral ischemia. "
|5.||Chronic Obstructive Pulmonary Disease (COPD)
05/01/2014 - "Our results indicate that aberrant DNA methylation is (1) a genome-wide phenomenon in small airways of patients with COPD, and (2) associated with altered expression of genes and pathways important to COPD, such as the NF-E2-related factor 2 oxidative response pathway. "
12/01/2012 - "Therefore, activation of the Nrf2 protein by small-molecule activators represents an attractive therapeutic strategy that is used for chronic obstructive pulmonary disease. "
02/01/2009 - "Immunoblot analysis revealed dramatic decreases in Srx1 expression in lungs from patients with COPD relative to nonemphysematous lungs together with a decline in Nrf2 protein. "
12/01/2008 - "Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease."
07/01/2008 - "Spearmint oil has protective effect on lung injury in COPD rats, since it improves pulmonary inflammation,oxidative alteration, and enhances Nrf2 protein expression."
|2.||Cytochrome P-450 CYP2E1 (CYP2E1)
|5.||Transcription Factors (Transcription Factor)
|6.||Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
|7.||Thymidine Monophosphate (TMP)
|3.||Heterologous Transplantation (Xenotransplantation)