MafG Transcription Factor

MafG is a ubiquitously expressed small maf protein that is involved in CELL DIFFERENTIATION of ERYTHROCYTES. It dimerizes with P45 NF-E2 PROTEIN and activates expression of ALPHA-GLOBIN and BETA-GLOBIN.

Also Known As:

Transcription Factor, MafG

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - Basic-Leucine Zipper Transcription Factors: 187
      - Maf Transcription Factors: 41
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein
      - NF-E2 Transcription Factor: 26
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein
    - Erythroid-Specific DNA-Binding Factors
      - NF-E2 Transcription Factor: 26
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein
  - DNA-Binding Proteins: 2009
    - Basic-Leucine Zipper Transcription Factors: 187
      - Maf Transcription Factors: 41
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein
      - NF-E2 Transcription Factor: 26
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein
    - Erythroid-Specific DNA-Binding Factors
      - NF-E2 Transcription Factor: 26
        Small Maf Transcription Factors: 1
        MafG Transcription Factor: 1
        human MAFG protein
        mouse Mafg protein
        rat Mafg protein

Related Diseases

1.	Infections 12/01/2023 - "Two such novel screen hits, the transcription factor MAFG and the transmembrane protein TMEM86A, were further validated as conferring resistance against SARS-CoV-2 by using CRISPR-mediated mutagenesis in hESCs, followed by differentiation of mutant lines into DE cells and infection by SARS-CoV-2. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)