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Farnesyltranstransferase (Farnesyltransferase)

An enzyme that catalyzes the synthesis of geranylgeranyl diphosphate from trans, trans-farnesyl diphosphate and isopentenyl diphosphate.
Also Known As:
Farnesyltransferase; Farnesyl Diphosphate-Geranylgeranyl Diphosphate Synthase; GGDP Synthase; GGPP Synthase; Geranylgeranyl Pyrophosphatase; Geranylgeranyl-Diphosphate Synthase; Farnesyl Diphosphate Geranylgeranyl Diphosphate Synthase; Geranylgeranyl Diphosphate Synthase; Pyrophosphatase, Geranylgeranyl; Synthase, GGDP; Synthase, GGPP; Synthase, Geranylgeranyl-Diphosphate
Networked: 374 relevant articles (22 outcomes, 79 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wright, John J: 11 articles (05/2014 - 04/2003)
2. Sebti, S M: 10 articles (02/2007 - 01/2000)
3. Sebti, Saïd M: 9 articles (05/2011 - 12/2003)
4. Hamilton, Andrew D: 9 articles (05/2011 - 01/2003)
5. Lancet, Jeffrey E: 9 articles (03/2011 - 07/2002)
6. Hamilton, A D: 9 articles (02/2007 - 01/2000)
7. Karp, Judith E: 8 articles (01/2014 - 07/2002)
8. Adjei, Alex A: 8 articles (01/2014 - 01/2002)
9. Sebti, Said M: 8 articles (01/2012 - 03/2002)
10. Kurzrock, Razelle: 8 articles (12/2010 - 07/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Leukemia
3. Breast Neoplasms (Breast Cancer)
4. Glioma (Gliomas)
5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

Related Drugs and Biologics

1. tipifarnib (R115777)
2. lonafarnib (SCH 66336)
3. Paclitaxel (Taxol)
4. taxane
5. Proteins (Proteins, Gene)
6. Tamoxifen
7. Estrogen Receptor Modulators (Antiestrogen)
8. letrozole (Femara)
9. Taxoids
10. Cyclin D1

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Molecular Targeted Therapy
3. Chemoprevention
4. Radiotherapy
5. Therapeutics