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Toll-Like Receptors (Toll-Like Receptor)

A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
Also Known As:
Toll-Like Receptor; Receptor, Toll-Like; Receptors, Toll Like; Toll Like Receptor; Toll Like Receptors; Receptors, Toll-Like
Networked: 4685 relevant articles (71 outcomes, 401 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Akira, Shizuo: 73 articles (08/2013 - 05/2002)
2. Anders, Hans-Joachim: 22 articles (09/2015 - 03/2004)
3. Flavell, Richard A: 21 articles (01/2015 - 07/2002)
4. Medzhitov, Ruslan: 21 articles (03/2013 - 07/2002)
5. Zacharowski, Kai: 18 articles (11/2015 - 11/2004)
6. Kirschning, Carsten J: 16 articles (10/2015 - 10/2002)
7. Szabo, Gyongyi: 16 articles (09/2013 - 11/2004)
8. Wagner, Hermann: 16 articles (08/2012 - 11/2003)
9. Netea, Mihai G: 15 articles (11/2015 - 05/2002)
10. van der Poll, Tom: 15 articles (01/2015 - 12/2004)

Related Diseases

1. Infection
2. Neoplasms (Cancer)
3. Inflammation
4. Colitis
5. Porcine Reproductive and Respiratory Syndrome (PRRS)

Related Drugs and Biologics

1. Ligands
2. Antigens
3. Vaccines
4. Cytokines
5. Interleukins
6. Interleukin-6 (Interleukin 6)
7. Messenger RNA (mRNA)
8. ProMune (CpG 7909)
9. bis(4-hydroxycinnamoyl)methane
10. Pattern Recognition Receptors

Related Therapies and Procedures

1. Immunotherapy
2. Drug Therapy (Chemotherapy)
3. Liver Transplantation
4. Resuscitation
5. Therapeutics