Selenium-Binding Proteins

A group of proteins that covalently attach to selenium or SELENIUM-containing compounds.

Also Known As:

Se-Binding Proteins; Binding Protein, Selenium; Protein, Se-Binding; Protein, Selenium Binding; Protein, Selenium-Binding; Se Binding Protein; Se Binding Proteins; Selenium Binding Proteins; Se-Binding Protein; Selenium Binding Protein; Selenium-Binding Protein

Networked: 80 relevant articles (0 outcomes, 9 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Selenium-Binding Proteins: 80

Experts

1.	Yang, Wancai: 9 articles (02/2015 - 11/2008)
2.	Diamond, Alan M: 8 articles (01/2020 - 04/2010)
3.	Schomburg, Lutz: 3 articles (01/2021 - 03/2019)
4.	Seelig, Julian: 3 articles (01/2021 - 03/2019)
5.	Fan, Jia: 3 articles (01/2018 - 06/2012)
6.	Huang, Cheng: 3 articles (01/2018 - 06/2012)
7.	Ji, Yuan: 3 articles (01/2018 - 06/2012)
8.	Zhou, Jian: 3 articles (01/2018 - 06/2012)
9.	Fang, Wenfeng: 3 articles (02/2015 - 11/2009)
10.	Ying, Qi: 3 articles (02/2015 - 01/2015)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "Recent studies have shown that selenium-binding protein 1 (SELENBP1) is significantly down-regulated in a variety of solid tumors. " 01/01/2018 - "Recent studies have found that selenium-binding protein 1 (SBP1) is downregulated in various malignant tumors. " 01/01/2015 - "Previous studies have shown the tumor-suppressive role of selenium-binding protein 1 (SBP1), but the underlying mechanisms are unclear. " 01/01/2022 - "SELENBP1 belongs to selenium-binding proteins and functions as a tumor suppressor. " 01/01/2021 - "Tumor suppressor activities of selenium-binding protein 1 (SELENBP1) have been shown in multiple human cancers except for OSCC. "
2.	Carcinogenesis 06/01/2006 - "Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival." 02/01/2010 - "The gradual loss of selenium-binding protein 1 associated with increasing epithelial proliferation and papillary complexity indicates that selenium-binding protein 1 is involved in tumorigenesis of ovarian serous borderline tumor, micropapillary serous borderline tumor, and low-grade serous carcinoma. " 12/09/2010 - "Our findings may provide a basis for future studies concerning the molecular mechanisms of selenium-binding protein 1 in tumorigenesis as well as the possible use of selenium in prevention and treatment of uterine leiomyoma." 12/09/2010 - "Decreased expression of selenium-binding protein 1 in uterine leiomyoma may indicate a role of the protein in tumorigenesis. " 10/17/2022 - "Selenium-binding protein 1 (SELENBP1), a member of the selenium-containing protein family, plays an important role in malignant tumorigenesis and progression. "
3.	Colorectal Neoplasms (Colorectal Cancer) 06/01/2014 - "The aim of the present study was to examine the regulation of selenium binding protein 1 (SELENBP1) expression in colorectal cancer (CRC). " 11/16/2009 - "Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts." 11/01/2008 - "We identified approximately 3.5-fold significant downregulation of selenium-binding protein 1 (SBP1) in colorectal tumors compared to normal mucosa (p = 0.003). " 11/01/2008 - "Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer." 10/17/2022 - "Tumor microenvironment-related gene selenium-binding protein 1 (SELENBP1) is associated with immunotherapy efficacy and survival in colorectal cancer."
4.	Carcinoma (Carcinomatosis) 12/01/2011 - "Altered expression of selenium-binding protein 1 in gastric carcinoma and precursor lesions." 06/01/2011 - "Reduced selenium-binding protein 1 is associated with poor survival rate in gastric carcinoma." 02/01/2010 - "Micropapillae and invasive carcinoma (including microinvasion) exhibited a near complete loss of selenium-binding protein 1 expression. " 06/01/2006 - "Among them, selenium-binding protein 1 (SELENBP1) was markedly decreased in 12 (85%) carcinomas. " 02/01/2010 - "The aim of the study was to examine by immunohistochemistry the expression of selenium-binding protein 1 in the various histologic components within ovarian serous borderline tumor, micropapillary serous borderline tumor, and low-grade serous carcinoma. "
5.	Prostatic Neoplasms (Prostate Cancer) 01/01/2020 - "The broad goal of the research described in this study was to investigate the contributions of selenium-binding protein 1 (SBP1) loss in prostate cancer development and outcome. " 01/01/2020 - "Selenium-binding protein 1 alters energy metabolism in prostate cancer cells." 01/01/2015 - "Evidence that selenium binding protein 1 is a tumor suppressor in prostate cancer." 07/15/1998 - "Using a subtractive approach called linker capture subtraction, we have found that the human selenium-binding protein gene hSP56 is differentially expressed by the relatively slow-growing, androgen-sensitive prostate cancer cell line LNCaP but not by the more rapidly growing androgen-insensitive lines PC-3 and DU145. " 07/15/1998 - "Differential expression and androgen regulation of the human selenium-binding protein gene hSP56 in prostate cancer cells."

Related Drugs and Biologics

1.	Selenium
2.	Proteins (Proteins, Gene)
3.	Glutathione Peroxidase GPX1
4.	Selenious Acid (Selenite)
5.	Biomarkers (Surrogate Marker)
6.	Messenger RNA (mRNA)
7.	tacrolimus binding protein 4 (FKBP52)
8.	Keratin-18 (Keratin 18)
9.	Selenoproteins (Selenoprotein)
10.	Peptide Elongation Factor 1 (EF-1)

Related Therapies and Procedures

1.	Chemoprevention
2.	Transjugular Intrahepatic Portasystemic Shunt
3.	Lasers (Laser)
4.	Immunotherapy
5.	Hysterectomy