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Serine C-Palmitoyltransferase

A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
Also Known As:
Long Chain Base Biosynthesis Protein 1; Long Chain Base Biosynthesis Protein 2; Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating); Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating); Serine Palmitoyltransferase; Serine Palmitoyltransferase 1; Serine Palmitoyltransferase 2; Serine Palmitoyltransferase, Long Chain Base Subunit 1; Serine Palmitoyltransferase, Long Chain Base Subunit 2; Serine-Palmitoyl-CoA Transferase 2; C-Palmitoyltransferase, Serine; Palmitoyltransferase 1, Serine; Palmitoyltransferase 2, Serine; Palmitoyltransferase, Serine; Serine C Palmitoyltransferase; Serine Palmitoyl CoA Transferase 2; Transferase 2, Serine-Palmitoyl-CoA
Networked: 46 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hornemann, Thorsten: 5 articles (05/2013 - 04/2009)
2. Timmerman, Vincent: 5 articles (05/2013 - 10/2002)
3. Nicholson, Garth A: 4 articles (07/2014 - 10/2002)
4. Auer-Grumbach, Michaela: 4 articles (05/2013 - 10/2002)
5. Park, Tae-Sik: 3 articles (07/2015 - 07/2008)
6. Penno, Anke: 3 articles (06/2011 - 04/2009)
7. Rotthier, Annelies: 3 articles (06/2011 - 04/2009)
8. Jiang, Xian-Cheng: 2 articles (09/2015 - 04/2013)
9. Geekiyanage, Hirosha: 2 articles (08/2013 - 10/2011)
10. Chan, Christina: 2 articles (08/2013 - 10/2011)

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Related Drugs and Biologics

1. GTP Phosphohydrolases (GTPases)
2. thermozymocidin (myriocin)
3. Apolipoproteins E (ApoE)
4. sphingosine kinase
5. Cytochrome P-450 CYP1A1 (CYP1A1)
6. Proteins (Proteins, Gene)
7. Glycosphingolipids
8. Cholesterol
9. Apolipoproteins
10. STF 62247