|1.||Bartus, Raymond T: 12 articles (08/2015 - 01/2007)|
|2.||Kordower, Jeffrey H: 9 articles (08/2015 - 05/2007)|
|3.||Herzog, Christopher D: 9 articles (01/2013 - 01/2007)|
|4.||Gasmi, Mehdi: 6 articles (04/2009 - 01/2007)|
|5.||Sun, Maosheng: 4 articles (01/2013 - 04/2003)|
|6.||Brown, Lamar: 4 articles (01/2013 - 04/2009)|
|7.||Li, Hongjun: 4 articles (01/2013 - 04/2003)|
|8.||Wilson, Alistair: 4 articles (10/2011 - 07/2007)|
|9.||Chen, Sheng-Di: 4 articles (01/2009 - 01/2007)|
|10.||Lu, Guo-Qiang: 4 articles (01/2009 - 01/2007)|
|1.||Parkinson Disease (Parkinson's Disease)
10/01/2008 - "Neurturin (NTN) is a neurotrophic factor for dopaminergic neurons that may be therapeutic for patients with Parkinson's disease (PD). "
12/01/2010 - "In an open-label phase 1 trial, gene delivery of the trophic factor neurturin via an adeno-associated type-2 vector (AAV2) was well tolerated and seemed to improve motor function in patients with advanced Parkinson's disease. "
05/01/2008 - "Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial."
08/30/2002 - "This study was designed to test the neuroprotective and regenerative effects of an intrastriatal injection of neurturin based on behavioral, neurochemical and histochemical changes in a rat model of progressive Parkinson's disease. "
08/01/2015 - "Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial."
12/01/2014 - "Visual analog scale pain scores significantly correlated with younger age, higher depression scores, increased expression of neurturin and decreased expression of transient receptor potential ankyrin 1 in the mucosa. "
02/01/2007 - "GDNF and neurturin have shown promise in clinical trials of Parkinson's disease, and artemin is currently undergoing clinical trials for chronic pain treatment. "
01/01/2011 - "In adult mammals, the phenotype of half of all pain-sensing (nociceptive) sensory neurons is tonically modulated by growth factors in the glial cell line-derived neurotrophic factor (GDNF) family that includes GDNF, artemin (ARTN) and neurturin (NRTN). "
07/24/2013 - "In contrast, GFRα1 and GFRα2 are not coexpressed with TRPM8 and their respective ligands GDNF and neurturin did not induce cold pain, whereas they did evoke heat hyperalgesia. "
|3.||Bipolar Disorder (Mania)
10/01/2008 - "In this study, we examined the expression levels of the members of the glial cell line-derived neurotrophic factor (GDNF) family (GDNF, artemin (ARTN), neurturin, and persephin), brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3 (NT-3), and neurotrophin-4 mRNAs by using quantitative real-time PCR method in peripheral blood cells of patients with major depressive and bipolar disorders in both a current depressive and a remissive states. "
|4.||Ganglion Cysts (Ganglion)
02/01/2009 - "In summary, neurturin-independent c-Jun expression within pelvic ganglion neurons does not require a direct injury and may instead be causally linked to axonal sprouting, regardless of stimulus. "
03/10/2008 - "Neurturin regulates postnatal differentiation of parasympathetic pelvic ganglion neurons, initial axonal projections, and maintenance of terminal fields in male urogenital organs."
10/01/1999 - "Multiple actions of neurturin correlate with spatiotemporal patterns of Ret expression in developing chick cranial ganglion neurons."
05/31/2004 - "Relatively little is known about the development of parasympathetic ganglia, but GDNF appears to play a role in the migration of some cranial ganglion precursors to their correct location, and both GDNF and neurturin are involved in the growth of parasympathetic axons into particular targets."
10/01/2001 - "Here, we show that glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN) constitute target-derived factors for developing ciliary ganglion neurons. "
|5.||Neurodegenerative Diseases (Neurodegenerative Disease)
01/01/2000 - "Therefore, our results suggest that neurturin is a good candidate for the treatment of this neurodegenerative disorder."
01/01/2013 - "Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating "clinical proof-of-concept" for AAV-neurturin (CERE-120) in Parkinson's disease."
04/01/2014 - "GDAs(BMP) produce multiple agents of interest as treatments for PD and other neurodegenerative disorders, including BDNF, GDNF, neurturin and IGF1. "
12/01/2000 - "Because GDNF and neurturin can rescue dopamine neurons in the animal models of Parkinson disease, as well as motoneurons in vivo, hopes have been raised that GDNF family ligands may be new drugs for the treatment of neurodegenerative diseases. "
02/04/2000 - "The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) (GDNF, neurturin, artemin, and persephin) are critical regulators of neurodevelopment and support the survival of midbrain dopaminergic and spinal motor neurons in vitro and in animal disease models making them attractive therapeutic candidates for treatment of neurodegenerative diseases. "
|1.||Glial Cell Line-Derived Neurotrophic Factor (GDNF)
|2.||Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
|4.||Brain-Derived Neurotrophic Factor (BDNF)
|6.||Nerve Growth Factor (NGF)
|9.||Nerve Growth Factors (Neurotrophins)
|10.||Glial Cell Line-Derived Neurotrophic Factors (GDNF Family Ligands)
|1.||Transplantation (Transplant Recipients)