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Proto-Oncogene Proteins c-akt (Protein Kinase B)

Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
Also Known As:
Protein Kinase B; AKT1 Protein Kinase; AKT2 Protein Kinase; AKT3 Protein Kinase; Akt-alpha Protein; Akt-beta Protein; Akt-gamma Protein; Protein Kinase B alpha; Protein Kinase B beta; Protein Kinase B gamma; Protein-Serine-Threonine Kinase (Rac); Proto-Oncogene Protein Akt; Proto-Oncogene Protein RAC; Proto-Oncogene Proteins c-akt1; Proto-Oncogene Proteins c-akt2; Proto-Oncogene Proteins c-akt3; RAC-PK Protein; Rac Protein Kinase; Rac-PK alpha Protein; Rac-PK beta Protein; Related to A and C-Protein; c-akt Proto-Oncogene Protein; Akt alpha Protein; Akt beta Protein; Akt gamma Protein; Akt, Proto-Oncogene Protein; Protein, akt Proto-Oncogene; Protein, c-akt Proto-Oncogene; Proteins c-akt1, Proto-Oncogene; Proteins c-akt2, Proto-Oncogene; Proteins c-akt3, Proto-Oncogene; Proto Oncogene Protein Akt; Proto Oncogene Protein RAC; Proto Oncogene Proteins c akt; Proto Oncogene Proteins c akt1; Proto Oncogene Proteins c akt2; Proto Oncogene Proteins c akt3; Proto-Oncogene Protein, akt; Proto-Oncogene Protein, c-akt; RAC PK Protein; RAC, Proto-Oncogene Protein; Rac PK alpha Protein; Rac PK beta Protein; Related to A and C Protein; akt Proto Oncogene Protein; alpha Protein, Rac-PK; c akt Proto Oncogene Protein; c-akt, Proto-Oncogene Proteins; c-akt1, Proto-Oncogene Proteins; c-akt2, Proto-Oncogene Proteins; c-akt3, Proto-Oncogene Proteins; akt Proto-Oncogene Protein; c-akt Protein
Networked: 2595 relevant articles (68 outcomes, 251 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wang, Wei: 15 articles (09/2022 - 02/2010)
2. Liu, Yang: 11 articles (03/2022 - 08/2003)
3. Zhang, Jing: 11 articles (01/2021 - 04/2008)
4. Li, Jing: 10 articles (07/2022 - 08/2013)
5. Zhang, Yan: 10 articles (06/2022 - 08/2006)
6. Zhang, Wei: 10 articles (01/2022 - 10/2016)
7. Maiese, Kenneth: 10 articles (01/2017 - 09/2004)
8. Wang, Tao: 8 articles (01/2022 - 05/2007)
9. Liu, Jun: 7 articles (03/2022 - 05/2015)
10. Li, Li: 7 articles (03/2022 - 01/2014)

Related Diseases

1. Insulin Resistance
2. Inflammation (Inflammations)
3. Reperfusion Injury
4. Neoplasms (Cancer)
5. Myocardial Ischemia (Ischemic Heart Diseases)

Related Drugs and Biologics

1. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2. TOR Serine-Threonine Kinases
3. Phosphotransferases (Kinase)
4. Insulin (Novolin)
5. Proteins (Proteins, Gene)
6. NF-kappa B (NF-kB)
7. Mitogen-Activated Protein Kinases
8. Glucose (Dextrose)
9. Insulin Receptor
10. Phosphatidylinositol 3-Kinases (PI 3 Kinase)

Related Therapies and Procedures

1. Therapeutics
2. Low-Level Light Therapy (LLLT)
3. Ovariectomy (Oophorectomy)
4. Aftercare (After-Treatment)
5. Drug Therapy (Chemotherapy)