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Diacylglycerol O-Acyltransferase

An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC 2.3.1.124.
Also Known As:
Acyl-Coenzyme A Diacyl-glycerol Acyltransferase; DAGAT Enzyme; Diacylglycerol Acyltransferase; Diacylglycerol O-Acyltransferase 1; Diglyceride Acyltransferase; Diglyceride Acyltransferase 1; Palmitoyl-CoA-sn-1,2-Diacylglycerol Acyltransferase; Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol Acyltransferase; A-sn-1,2-Diacylglycerol Acyltransferase, Palmitoyl-Coenzyme; Acyl Coenzyme A Diacyl glycerol Acyltransferase; Acyltransferase 1, Diglyceride; Acyltransferase, Diacylglycerol; Acyltransferase, Diglyceride; Acyltransferase, Palmitoyl-CoA-sn-1,2-Diacylglycerol; Acyltransferase, Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol; Diacylglycerol O Acyltransferase; Diacylglycerol O Acyltransferase 1; O-Acyltransferase 1, Diacylglycerol; O-Acyltransferase, Diacylglycerol; Palmitoyl CoA sn 1,2 Diacylglycerol Acyltransferase; Palmitoyl Coenzyme A sn 1,2 Diacylglycerol Acyltransferase
Networked: 63 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Farese, Robert V: 10 articles (10/2014 - 08/2002)
2. Lee, Hyun Sun: 6 articles (11/2014 - 12/2006)
3. Chen, Hubert C: 4 articles (06/2003 - 08/2002)
4. Zhou, Ping: 3 articles (01/2012 - 11/2002)
5. Lees, David: 2 articles (04/2015 - 01/2013)
6. Turnbull, Andrew V: 2 articles (10/2014 - 01/2013)
7. Knutsson, M: 2 articles (04/2014 - 02/2013)
8. Denison, H: 2 articles (04/2014 - 02/2013)
9. Löfgren, L: 2 articles (04/2014 - 02/2013)
10. Eriksson, J W: 2 articles (04/2014 - 02/2013)

Related Diseases

1. Obesity
2. Hyperlipidemias (Hyperlipidemia)
3. Fatty Liver
4. Body Weight (Weight, Body)
5. Insulin Resistance

Related Drugs and Biologics

1. Acyl Coenzyme A (Acyl CoA)
2. Coenzyme A (CoA)
3. Antisense Oligonucleotides
4. microsomal triglyceride transfer protein
5. Incretins
6. Apolipoprotein C-III
7. Apolipoprotein B-100 (Apo B 100)
8. Dietary Fats (Ghee)
9. Triglycerides (Triacylglycerol)
10. Enzymes